DIAGNOSTIC RADIOGRAPHY · NTA LEVEL 4 · SEMESTER TWO Common Gynecological Anomalies – Part 1 CRT04210 · Ultrasound Imaging START READING NOTES Study Common Gynecological Anomalies – Part 1 using the sections below. Use the topic navigation to continue through Ultrasound Imaging. Contents of This Topic Common Gynaecological Anomalies- Part 1 UTERUS TECHNIQUE CONGENITAL ANOMALIES Septate/arcuate uterus Bicornuate uterus Uterine didelphys Differentiation requires visualization of Less divergence of endometrial stripes SEPTATE UTERUS Endocrine causes Primary amenorrhea 3.Pelvic inflammatory disease (PID) A.Pelvic Inflammatory Disease: US Findings B.Endometritis Indistinct, thickened endometrial stripe, +/- fluid, air C.Pelvic Inflammatory Disease (PID) Hydrosalpinx (Hydrosalpingitis) US Findings :Complex, multicystic, thick walled mass, internal echoes TOA: US Findings Complex, multicystic, thick walled mass, internal echoes 4.Uterine Fibroids Uterine Fibroids Risk factors: the following factors are predisposing Fibroids (Leiomyomas) Types of Fibroids TYPES(LOCATION) OF LEIOMYOMAS (FIBROIDS) Location of Fibroids Fibroids: US Findings Fibroid Pedunculated LEIOMYOMA- Calcifications in Pedunculated subserosal leiomyoma Complications of Fibroids: Benign neoplasm Hormonally responsive 7.Uterine Sarcoma Ectopic endometrium located within the myometrium Adenomyosis Pt presentation: Adenomyosis: US Findings Think adenomyosis: Think leiomyoma (Fibroid): 8.Endometrial Hyperplasia, and Polyps 10.Abnormal bleeding in postmenopausal women 11.Endometrial carcinoma 12.Cervical Mass 12.Abnormal Vagina 12.Intrauterine Device (IUD) Intrauterine Device (IUD) Echogenic, shadowing, linear structure in endometrial cavity Common Gynaecological Anomalies- Part 1 MDU,BMI,ECHO&ECG,DDR UTERUS Outline- Uterine Pathologies Technique Normal anatomy Congenital anomalies Leiomyoma/Fibroids Pelvic Inflamatory Disease Adenomyosis Endometrial Hyperplasia and polyps. Postmenopausal uterus- Endometrial Ca TECHNIQUE Endovaginal improved spatial resolution smaller field of view Transabdominal imaging complementary enlarged uterus congenital anomalies evaluation of the kidneys MRI/HSG may provide more specific information in selected cases Review of normal Anatomy 1.CONGENITAL ANOMALIES CONGENITAL ANOMALIES Incidence 0.1% to 0.5% all women 9% in women with infertility or fetal loss Associated with renal anomalies Defects include: Septate/arcuate uterus Unicornuate uterus Bicornuate uterus Uterine didelphys Septate/arcuate uterus Has a normal external surface but two endometrial cavities Degree of septation varies from a small midline septum to total septate uterus with longitudinal vaginal septum Arcuate has slight midline septum with minimal fundal cavity indentation Unicornuate uterus Bicornuate uterus Uterus in which the fundus is indented (≥1 cm) and the vagina is generally normal. Results from only partial fusion of the müllerian ducts Leads to a variable degree of separation of the uterine horns that can be complete, partial, or minimal. Uterine didelphys “double uterus” duplication is limited to the uterus (didelphys) and cervix (bicollis) although other structures (vagina, bladder, etc may be involved) Differentiation requires visualization of endometrial stripes fundal contour Visualization of fundal contour may require Transabdominal Ultrasound or 3 dimensional ultrasound SEPTATE VS. BICORNUATE UTERUS BICORNUATE UTERUS Divergent endometrial stripes > 1.0 to 1.5 cm cleft between horns BICORNUATE UTERUS Divergent endometrial stripes > 1.0 to 1.5 cm cleft between horns X > 1.5 cm Bicornuate uterus ( Double Endometrium) Less divergence of endometrial stripes Flat, convex, or minimally indented fundal contour (< 1 cm) SEPTATE UTERUS SEPTATE UTERUS SEPTATE UTERUS X < 1.0 – 1.5 cm Endocrine causes Absence, atresia or obstruction of vagina, cervix, or uterus +/- Pelvic mass Role of imaging confirm level of abnormality extent of vagina presence / absence of uterus and cervix 2.Primary amenorrhea Primary amenorrhea Uterine Agenesis Note: No Uterus posterior to UBL Primary amenorrhea Haematocolpos in imperforate Hymen Note: Blood collection in Uterine cavity(HAEMATOMETRA) 3.Pelvic inflammatory disease (PID) Ascending infection that may involve the uterus(endometrium), fallopian tubes, ovaries, and pelvic cavity, and may produce tubo-ovarian abscesses(TOA) Presents with LAP, Fever, PV discharge, Cervical motion tenderness A.Pelvic Inflammatory Disease: US Findings Endometritis (Endometrial fluid) Hydrosalpinx: Dilated fallopian tube Thickened, inflamed fallopian tube +/- internal echoes (pyosalpinx)- Pus fillled Tubo – Ovarian Abscess Fluid in cul-de-sac (Pouch of Douglas) B.Endometritis Sx: fever, leukocytosis, tenderness, foul smelling discharge Occurs post partum, following D&C, PID Indistinct, thickened endometrial stripe, +/- fluid, air post partum findings RPOC Endometritis: US Findings Endometritis (Fluid in Endometrium) C.Pelvic Inflammatory Disease (PID) Fluid in pouch of Douglas Significant Fluid > 1cm deepest pool D.Hydrosalpinx (salpingitis) Hydrosalpinx (Hydrosalpingitis) Infection of fallopian tubes Dilated, tubular, anechoic structure between uterus and ovary E.PYOSALPINX US Findings :Complex, multicystic, thick walled mass, internal echoes F.(Tubo-ovarian cyst)-TOA: TOA: US Findings Often bilateral Ovarian margins may be indistinct ovary relatively spared Complex, multicystic, thick walled mass, internal echoes TOA: US Findings 4.Uterine Fibroids Definition Are benign monoclonal tumors arising from the smooth muscle cells of the myometrium, termed leiomyoma. They contain a large amount of extracellular matrix (collagen, proteoglycan, fibronectin) and are surrounded by a thin pseudocapsule of areolar tissue and compressed muscle fibers. Synonyms: fibroid or fibromyoma. Incidence: The most common gynecological tumors in about 30% of women of reproductive age. 20% of women after 30 years develop uterine fibroid. More prevalent in black African women Uterine Fibroids Etiology: The possible etiology is hyperestrinism (estrogen-dependent tumor). The evidences supporting this include: Associated with exposure to circulating estrogen (arise during adulthood) Shrink following menopause Maximum growth when estrogen secretion is maximal, spurt in growth in the decade before menopause (an ovulatory cycles with unopposed estrogen) Increased growth during pregnancy (caused by estrogen) Estrogen receptors are more in leiomyoma compared to the rest of myometrium N.B. Growth factors may act synergistically with estrogen to induce growth of myoma Risk factors: the following factors are predisposing Age: common between 35 & 45 years. Parity: common in nulliparous or low porous & relatively infertile women. Race: common in black women Family history : +ve. Obesity Early menarche (<10 years old) A longer interval since last birth increases risk Consumption of alcohol, especially beer, appears to increase the risk of developing fibroids however smoking decreases the risk of having fibroids. Significant consumption of beef, ham, or other red meats is associated with an increased relative risk of fibroids Protective factors Early age at first birth decreases risk consumption of green vegetables with a decreased risk Fibroids (Leiomyomas) Fibroids are benign tumors of the uterus arising from the Myometrium Smooth muscle neoplasms Patients Presentation Asymptomatic Abnormal Uterine bleeding- Menorrhagia Pelvic pain Infertility Abortions ( Submucosal and Intramural