DIAGNOSTIC RADIOGRAPHY · NTA LEVEL 4 · SEMESTER TWO Ultrasound of the Ovary and Endometrium CRT04210 · Ultrasound Imaging START READING NOTES Study Ultrasound of the Ovary and Endometrium using the sections below. Use the topic navigation to continue through Ultrasound Imaging. Contents of This Topic THE MENSTRUAL CYCLE The first menstrual cycle is termed menarche. Menarche occurs at different ages and may be influenced by environment and diet. Ultrasound of the Ovary and Endometrium THE PHYSIOLOGY OF THE OVARIAN CYCLE THE PHYSIOLOGY OF THE ENDOMETRIAL CYCLE During the first half of the menstrual cycle, the endometrium undergoes thickening as a result of estrogen stimulation. SONOGRAPHIC APPEARANCES OF THE ENDOMETRIUM This finding is referred to as the three-line sign. Following ovulation, the secretory endometrium is maintained by the DISRUPTION OF THE MENSTRUAL CYCLE BY PREGNANCY ENDOMETRIAL PATHOLOGY The endometrium will appear thin and will not measure more than 5 mm .It may also contain some intracavitary fluid. Endometrial Hyperplasia Endometrial Carcinoma ANATOMY AND PHYSIOLOGY OF THE OVARY The cells surrounding the tiny follicles produce estrogen, which stimulates the endometrium to thicken. PATHOLOGY OF THE OVARY Corpus Luteum Cysts Cystic Teratoma (Dermoid) Endometrioma (Chocolate Cyst) THE MENSTRUAL CYCLE The last menstrual period relates to the onset of menses; therefore, the first day of the menstrual cycle is said to occur on the first day of bleeding. The average menstrual cycle lasts 28 days, with ovulation typically occurring around day 14. However, some menstrual cycles may last only 25 days while others may last up to 45 days. 1 Days 1 through 5 of the menstrual cycle correlate with menses, at which time the endometrium is shed. The first menstrual cycle is termed menarche. Menarche occurs at different ages and may be influenced by environment and diet. However, if an individual does not experience menarche before age 16, she is said to have primary amenorrhea. Ultrasound of the Ovary and Endometrium Primary amenorrhea may be caused by congenital abnormalities or congenital obstructions, such as an imperforate hymen. Secondary amenorrhea may be associated with endocrinologic abnormalities or pregnancy. Secondary amenorrhea that is not associated with pregnancy is characteristically diagnosed in the postmenarchal woman who has had at least 12 months without a menstrual cycle THE PHYSIOLOGY OF THE OVARIAN CYCLE The ovarian cycle consists of two phases: the follicular phase and the luteal phase. The follicular phase of the ovarian cycle is considered to begin on day 1 and lasts until day 14, thus, in effect, ending with ovulation. During the follicular phase, the anterior pituitary gland secretes FSH, which initiates the follicular development of the ovary. Ultrasound of the Ovary and Endometrium Many follicles are produced by the ovary. While numerous follicles manifest, only one follicle will be maintained and become the graafian follicle or dominant follicle prior to ovulation. This graafian follicle, which can grow as large as 2.7 cm, contains the developing oocyte (egg) within a region called the cumulus oophorus. Ultrasound of the Ovary and Endometrium Around day 14, LH, produced by the anterior pitu itary gland, stimulates ovulation, at which time the graafian follicle, which has grown to a size of 15 to 27 mm, ruptures and expels a small amount of fluid and the ovum into the peritoneum. The ovum is picked up by the fimbria of the fallopian tube and is propelled through the tube, either to be fertilized, resorbed by the body, or passed with menstruation. Ultrasound of the Ovary and Endometrium The second phase of the ovarian cycle, days 15 to 28, is termed the luteal phase. After the graafian follicle ruptures, it is temporarily turned into an endocrine gland in the form of the corpus luteum. The corpus luteum, while producing estrogen in small amounts, primarily produces progesterone to maintain the thickness of the endometrium and prepare the endometrium for the (conceivably) fertilized ovum. All the other follicles undergo atresia. Ultrasound of the Ovary and Endometrium While the corpus luteum depends on LH to be maintained, progesterone negatively inhibits the production of LH by the anterior pituitary gland, resulting in the regression of the corpus luteum. The remaining structure of the corpus luteum is now termed the corpus albicans, which can often be seen sonographically as a small echogenic scar on the ovary.1 THE PHYSIOLOGY OF THE ENDOMETRIAL CYCLE The endometrium has two basic layers. The innermost portion, the functional layer, is the layer that changes throughout the menstrual cycle. The functional layer provides an appropriate location for implantation to occur. The outermost portion, the basal layer, is only slightly altered during the menstrual cycle. It consists of dense, cellular stroma Ultrasound of the Ovary and Endometrium The endometrial cycle consists of two phases: the proliferative phase and the secretory phase. The proliferative phase occurs after menstruation and lasts until ovulation. The endometrium is influenced by estrogen and progesterone, which are produced by the ovary. During the first half of the menstrual cycle, the endometrium undergoes thickening as a result of estrogen stimulation. Thus, proliferation of the endometrium, which is described as the multiplication of similar forms, occurs during the proliferative phase of the endometrial cycle, as the functional layer increases in thickness. Ultrasound of the Ovary and Endometrium The secretory phase of the endometrial cycle occurs after ovulation and is stimulated by progesterone. Progesterone maintains the thickness of the endometrium in preparation for implantation. Should fertilization not take place, menses begin on day 1 of the cycle, resulting from a lack of estrogen and proges terone. Ultrasound of the Ovary and Endometrium Conversely, if fertilization does occur, the en dometrial thickness is maintained by the continual production of progesterone by the corpus luteum of pregnancy SONOGRAPHIC APPEARANCES OF THE ENDOMETRIUM As the hormones produced by the ovary act upon the endometrium, the thickness of the endometrium varies. Consequently, the sonographic appearance of the endometrium changes Following menses, the endometrium appears as a thin, echogenic line Ultrasound of the Ovary and Endometrium Thus, the early proliferative endometrium appears echogenic and thin and