Acid – Base Balances and Common Electrolyte Disorders – PST04103 Human Anatomy and Physiology
NTA Level 4 • Semester 1 • PST04103 Acid – Base Balances and Common Electrolyte Disorders Human Anatomy and Physiology • Source Session/Topic 21 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 21: Acid – Base Balances and Common Electrolyte Disorders Total Session Time: 120 minutes Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Define Acidity ,Alkalinity and pH • Describe Acid Base Balance • Describe Acidosis and Alkalosis • Describe Electrolyte Disorders • Describe Oedema and Ascites Resources Needed: • Flip charts, marker pens, and masking tape • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Overhead Projector and Transparencies or Slide Projector/LCD and Computer • Hand out 17.1:Oedema and Ascites SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | |2 |25 minutes |Presentation | Acid, Base and Acid Base Balance | | | |Brainstorming | | |3 |15 minutes |Presentation |Acidosis and Alkalosis | |4 |50 minutes |Presentation |Common Electrolyte Disorders | | | |Small Group | | |5 |15 minutes |Presentation |Oedema and Ascites | |6 |05 minutes |Presentation |Key Points | | 7 |05 minutes |Presentation |Evaluation | SESSION CONTENTS STEP 1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Acid Base Balance (25 minutes) |Activity: Brainstorming (5 minutes) | | | |Ask students to brainstorm on the following questions: | | | |What is acidity? | |What is alkalinity? | |What is pH? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • Acidity is the term which expresses the concentration of Hydrogen ion (H+) of any substance in aqueous solution or the body fluids. • Alkalinity is the term used to express the concentration of Hydroxyl ions (OH-) or the salinity of any substance in aqueous solution or the body fluids. • pH is the scale used to determine the acidity or the alkalinity of the body fluids • The higher the pH the less the acid the substance is and lower the pH the more the acid the substance is. The Body pH • Optimum pH is maintained by keeping the balance between acids and bases produced by the body cells. • There is an inbuilt mechanism which ensures that excess acid or alkali is safely eliminated from the body, better known as the buffer system. • The organs most active in this activity are the lungs and the kidneys. • In order to maintain normal blood pH the cells of the proximal convoluted tubules secret hydrogen ions. In the filtrate hydrogen ions combine with buffers o Bicarbonate forming carbonic acid o Ammonia forming ammonium ions o Hydrogen phosphate forming dihydrogen phosphate • Carbonic acid is converted to carbon dioxide (CO2) and water (H2O), carbon dioxide is reabsorbed, maintaining the buffering capacity of the blood. • Hydrogen ions are lost through urine as ammonium salts and hydrogen sulphate. • Other buffer systems include body proteins and phosphates which absorb excess hydrogen ions (H+). • The lungs regulate the blood pH by either increasing or decreasing the amount of carbon dioxide lost (increased or decreased respiration). • Carbon dioxide combine with water to form carbonic acid, which eventually dissociates to bicarbonates and hydrogen ions thus lowering the body pH. • Therefore any condition which retains carbon dioxide in the body will increase the blood acidy and vice versa. • Kidneys regulate blood pH by controlling the amount of hydrogen ion lost through urine. • The normal blood pH ranges from 7. 35 to 7.45. STEP 3: Acidosis and Alkalosis (15 minutes) • The buffer systems described above compensate for most of pH fluctuations, but these reserves are limited and in extreme cases, can become exhausted • When the blood pH falls below 7.35 and all the reserves of alkaline buffers are consumed, the condition of acidosis exists • In the opposite manner when the pH rises above 7.45, the increased alkali uses up all the acid reserve and the state of alkalosis ensues • Acidosis and alkalosis are both injurious to the body, particularly to the central nervous and cardiovascular systems. In practice acidotic states are more common than alkalotic ones, because the body tends to produce more acid than alkali • Acidosis may follow respiratory problems, if lungs are not excreting CO2 as efficiently as normal, or if the body is producing excess acid as in diabetic ketoacidosis or in renal diseases when kidneys are not excreting H+ as normal • Alkalosis may be caused by loss of basic substances as in vomiting or diarrhoea, and rarely through hyperventilation (excess CO2 loss) STEP 4: Electrolyte Disorders (50 minutes) |Activity: Small Group Discussion ( 30 minutes) | | | |DIVIDE students into small manageable groups | | | |ASK students to discuss on the following question | | | |What are the common electrolyte disorders? | | | |ALLOW students to discuss for 15 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |CLARIFY and SUMMARIZE by using the contents below | • An electrolyte disorder is an imbalance of certain ionized salts( which include bicarbonate, calcium, chloride, magnesium, phosphate, potassium , and sodium) in the blood Sodium • Hypernatremia refers to a high sodium concentration in the blood than normal. • Hypernatremia can be caused by inadequate water intake, excessive fluid loss kidneydisease, severe burns, and prolonged vomiting or diarrhea), or sodium retention (caused by excessive sodium intake oraldosteronism ). • Hyponatremia refers to low sodium concentration