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Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Malaria – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Malaria Disease Control and Prevention • Source Session/Topic 15 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 15: Identification of Patients with Malaria Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session studentsare expected to be able to: • Describe Causes of Malaria, • Describe Mode of Transmission of Malaria • Describe Major Signs and Symptoms of Malaria • Explain Treatment of Malaria • Explain Prevention and Control of Malaria Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD projector • Handout 15.1; Life cycle of malaria parasite • Handout 15.2; Treatment of uncomplicated malaria SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |5 minutes |Presentation |Cause(s) of Malaria | |3 |30 minutes |Presentation |Mode of Transmission of Malaria | |4 |15 minutes |Presentation |Major Signs and Symptoms of Malaria | | | |Brainstorming | | |5 |30 minutes |Presentation |Treatment of Malaria | |6 |20 minutes |Presentation |Prevention and Control of Malaria | | | |Buzzing | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP 1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Malaria (5 minutes) Malaria • An acute infection of the blood caused by protozoa of genus Plasmodium • Malaria is the most common disease in the tropical Africa Causative Agents of Malaria There are 4 different species of Malaria parasite which infect human beings: • Plasmodium falciparum (commonest cause of Malaria in Tanzania) • Plasmodium Malariae • Plasmodium vivax • Plasmodium ovale STEP 3: Mode of Transmission of Malaria (30 minutes) • Malaria is transmitted by the female Anopheles mosquito which requires human blood for the development of eggs. • The male mosquito does not suck human blood. • Major Anopheles species of importance in Africa include: o Anopheles Gambiae -Most important vector in Africa. o Anopheles Funestus – Breeds in permanent vegetation e.g. swamps. [pic] Figure 15.1 Spread of malaria Life cycle of malaria parasite • Divided into two phases o Asexual cycle occurring in human o Sexual or sporogony cycle occurring in female Anopheles (mosquito) Life Cycle of Malaria Parasites in Man (Asexual Cycle) • Sporozoites in the mosquito salivary glands are injected into the host via the proboscis of the mosquito • They quickly migrate to the liver • The hepatic (Liver) stage o The Sporozoites is taken up by the Kupffer cells of the liver and then passes through into the hepatocytes or liver cells o There, it develops into hepatic Schizont, releasing thousands of Merozoites into the general circulation • Hypnozoites o This stage of the parasites only occurs in Plasmodium Ovale and Plasmodium Vivax o The Hypnozoites mature unpredictably and releases new Merozoites responsible for recurrent infections up to 18 months after primary infection, even though earlier blood stages may have been cured o Without treatment (specific) using primaquine, it is thought that this stage may remain in the liver for life • Erythrocytic or Blood Stage o The merozoites released from the liver invade individual red blood cells (RBCs) and then develop within the RBCs from “rings” into blood schizonts o The schizonts then rupture the RBCs releasing numerous merozoites which invade new RBCs o It is this part of the cycle that causes clinical illness, and then Length of time for each RBC cycle gives the periodicity of the symptoms • Gametocytes o At unknown stage or time in the RBCs cycle, ‘sexual’ forms develop and are in turn responsible for the survival and transmission of the parasite o Male and female gametocytes circulate for a few weeks and are taken up by the feeding mosquito Life Cycle of Malaria Parasites in Mosquito (Sexual Cycle of Malaria Parasites) • Sexual reproduction, the male and female gametocytes develop into gametes and then fuse in the stomach of mosquito to form a zygote • This develops into a mobile ookinete which immigrates through the wall of the stomach to form an oocyst • Oocyst matures and releases sprorozoites • Sporozoites migrate to the salivary glands ready for delivery with the mosquito’s next meal [pic]Refer to handout 15.1: Life Cycle of Malaria Parasite STEP 4: Major Signs and Symptoms of Malaria (15 minutes) |Activity: Brainstorming (5 minutes) | | | |ASK students to brainstorm on the following question | | | |What are the major signs and symptoms of Malaria? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | Signs and symptoms of Malaria The signs and symptoms of Malaria are non–specific and can mimic symptoms of systemic viral illnesses or other disease condition. The occurrence of Malaria signs and symptoms may differ in children and adults Signs and symptoms of uncomplicated Malaria • Fever • Headache • Malaise • Joint pains • Vomiting /diarrhoea • Body ache • Poor appetite • Body weakness • Pallor • Enlarged spleen Signs and symptoms of Severe Malaria • Extreme weakness • Impaired consciousness • Change of behaviour ( hallucinations, delusions, agitation, and acute state of confusion) • Respiratory distress • Bleeding tendency • Jaundice • Circulatory collapse/ shock • Vomiting everything • Inability to drink or breastfeed STEP 5: Treatment of Malaria (30 minutes) Treatment of Uncomplicated Malaria with First Line Drugs • Artemether/ Lumefantrine (ALU) an oral fixed combination tablet of 20 mg Artemether (a derivative of artemisinin) and 120

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Common Cold – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Common Cold Disease Control and Prevention • Source Session/Topic 16 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 16: Identification of Patients with Common Cold Total Session Time: 60 minutes + 1 hour Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Cause of Common Cold, • Describe Mode of Transmission of Common Cold • Describe Major Signs and Symptoms of Common Cold • Explain Treatment of Common Cold • Explain Prevention and Control of Common Cold Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |10 minutes |Presentation |Causes of Common Cold | | | |Buzzing | | |3 |5 minutes |Presentation |Mode of Transmission of Common Cold| |4 |5 minutes |Presentation |Major Signs and Symptoms of Common | | | | |Cold | |5 |10 minutes |Presentation |Treatment of Common Cold | | | |Brainstorming | | |6 |10 minutes |Presentation |Prevention and Control of Common | | | | |Cold | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Task (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Common Cold (10 minutes) An introduction to URTI • Respiratory tract infection: A term used to describe infection of all the parts of the body that are involved in helping a person to breathe • Upper Respiratory Tract include the nose, sinuses, pharynx and trachea • Respiratory tract infection can be divided into: o Upper respiratory tract infection o Lower respiratory tract infection • Common upper respiratory tract infections (URTIs) include: o Common cold o Sore throat – usually due to an infection of the pharynx (pharyngitis) o Tonsillitis – infection of the tonsils o Sinusitis – infection of the sinuses o Laryngitis – infection of the larynx This session will deal with Common cold Common cold (Coryza) Cause: Is caused by a number of viruses which are spread by droplets and by indirect transmission such as through freshly infected articles (handkerchiefs) STEP 3: Mode of Transmission of Common Cold (5 minutes) • Droplet infection through talks, coughs, laughs, or sneeze discharges • Causative microorganisms is carried in droplets from infected person to another via respiratory tract • Airborne disease spread more easily when there is overcrowding STEP 4: Major Signs and Symptoms of Common Cold (5 minutes) • Running nose and sneezing • Fever • Malaise • Headache • Running eye • Nasal congestion • Sore throat • Cough STEP 5: Treatment of Common Cold (10 minutes) |Activity: Brainstorming (5 minutes) | | | |ASK students to brainstorm on the following question: | | | |What is the treatment of common cold? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • No effective treatment is available.Headache may be relieved by analgesics • Nasal congestion may temporarily be relieved by Ephedrine nose drop STEP 6: Prevention and Control of Common Cold (10 minutes) • Prevent droplet infection from being inhaled by others • Improve ventilation for example building houses with adequate window to allow natural air flow • Avoid overcrowding e.g. building houses with enough space • Isolation may be required for some conditions • Health education about personal hygiene, such as: o To cover the mouth when coughing and sneezing o Use handkerchief or paper for disposal of nasal secretion and sputum o Avoid to spit on the ground or outside the house o Avoid sharing cigarettes, drinking bowels, or eating utensils • Wearing of masks in the hospitals • Immunization STEP 6: Key Points (5 minutes) • Among the common Upper Respiratory Tract infections includes Common cold • Common cold is caused by viruses • Treatment is symptomatic in most cases • Prevention and control include improved ventilation, avoiding overcrowding, personal hygiene and immunization STEP 7: Evaluation (5 minutes) • What is the cause of common cold? • What is the mode of transmission for common cold? • What are major signs and symptoms of common cold? • What is the treatment for common cold? • What are the prevention and control measures of common cold? STEP 8: Assignment (5 minutes) |Activity: Take Home Assignment (5 minutes) | | | |DIVIDE individual assignment | | | |ASK the students to work individually on the following Assignment | |Prepare a presentation on how to prevent common cold in their location | | | |ALLOCATE time for students to do the assignments and submit | | | |REFER students to recommended reference | References Cook, G., & Zumla, A. (2003). Manson’s Tropical Diseases. (21sted.). London: Saunders Ltd Denyer, S. P., Hodges, N. A., Gorman, S. P., & Gilmore BF (2011) (Eds.).Hugo & Russell’s Pharmaceutical Microbiology (8thed). Oxford: Willey- Blackwell Publishing Eshuis J., & Manschot, P (1992). Communicable Diseases,(1st ed). Nairobi: AMREF GoT (2004): National Infection Prevention and Control (IPC) Guidelines for Healthcare Workers. Dar es Salaam: MOHSW GoT (2013) Standard Treatment Guidelines & National Essential Medicines List (4 ed). Dar es Salaam: MOHSW Nordberg, E. (1999): Communicable Diseases, A Manual for Health Workers in Sub-Saharan Africa, Nairobi: AMREF Nordberg, E., Kingondu, T., & Mugambi, E., et al. (2008) Communicable Diseases. (4th ed.). Nairobi: AMREF ← Previous TopicNext Topic →View all Disease Control and Prevention topicsOpen Complete Full Notes PDF / OFFLINE NOTES Unataka kutumiwa notes hizi kupitia WhatsApp?Kwa notes

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Tonsillitis – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Tonsillitis Disease Control and Prevention • Source Session/Topic 17 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 17: Identification of Patients with Tonsillitis Total Session Time: 60 minutes + 1 hour Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Causes of Tonsillitis • Describe Mode of tansmission of Tonsillitis • Describe Major Signs and Symptoms of Tonsillitis • Explain Treatment of Tonsillitis • Explain Prevention and Control of Tonsillitis Resources Needed: • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |5 minutes |Presentation |Cause(s) of Tonsillitis, | |3 |5 minutes |Presentation |Mode of Transmission of Tonsillitis| |4 |10 minutes |Presentation |Major Signs and Symptoms of | | | |Brainstorming |Tonsillitis | |5 |5 minutes |Presentation |Treatment of Tonsillitis | |6 |15 minutes |Presentation |Prevention and Control of | | | |Buzzing |Tonsillitis | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Tonsillitis (5 minutes) Tonsillitis At the back of throat, two masses of tissue called tonsils act as filters, trapping germs that could otherwise enter the airways and cause infection. They also produce antibodies to fight infection. But sometimes the tonsils themselves become infected, they swell and become inflamed, a condition known as tonsillitis Causes • Streptococcal bacteria • Viruses can also cause acute tonsillitis STEP 3: Mode of Transmission of Tonsillitis (5 minutes) • Droplet infection through talks, coughs, laughs, or sneezes discharges • Causative microorganism is carried in droplets from infected person to another via respiratory tract • Airborne disease spread more easily when there is overcrowding STEP 4: Major Signs and Symptoms of Tonsillitis (10 minutes) |Activity: Brainstorming (5 minutes) | | | |Ask students to brainstorm on the following question: | | | |What are the major signs and symptoms of Tonsillitis? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | Major signs and symptoms of Tonsillitis • Sudden onset with general malaise • Fever • Headache • Sore throat and difficult in swallowing • Signs of inflammation e.g. redness of tonsils and white spots STEP 5: Treatment of Tonsillitis (5 minutes) • Symptomatic treatment • Bed rest is advised • Light diet with plenty of hot drinks • Analgesics such as paracetamol to reduce pain and fever STEP 6: Prevention and Control of Tonsillitis (15 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What are the methods for preventing and controlling Tonsillitis? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Prevent droplet infection from being inhaled by others • Improve ventilation such as building houses with adequate window to allow natural air flow • Avoid overcrowding for example building houses with enough space • Isolation may be required for some conditions • Health education about personal hygiene e.g. o To cover the mouth when coughing and sneezing o Use handkerchief or paper for disposal of nasal secretion and sputum o Avoid to spit on the ground or outside the house o Avoid sharing cigarettes, drinking bowels, or eating utensils • Wearing of masks in the hospitals • Immunization STEP 6: Key Points (5 minutes) • Tonsillitis is caused by bacteria and also viruses transmitted by droplets • Treatment is symptomatic in most cases • Prevention and control include improved ventilation, avoiding overcrowding, personal hygiene and immunization STEP 7: Evaluation (5 minutes) • What are causes of Tonsillitis? • What is the mode of transmission for Tonsillitis? • What are major signs and symptoms of Tonsillitis? • What is the treatment for common Tonsillitis? • What are the prevention and control measures of Tonsillitis? STEP 8: Assignment (5 minutes) |Activity: Take Home Assignment (5 minutes) | | | |ASK the students to work individually on the following Assignment | |Prepare a presentation on how to prevent Tonsillitis in their location | | | |ALLOCATE time for students to do the assignments and submit | | | |REFER students to recommended reference | References Cook, G&. Zumla, A. (2003). Manson’s Tropical Diseases. (21sted.). London: Saunders Ltd Denyer, S. P. Hodges, N. A. & Gorman, S. P (2011) Ed. Hugo & Russell’s Pharmaceutical Microbiology (8thed). Oxford: Willey-Blackwel publishing Eshuis, J.& Manschot,P (1992). Communicable diseases,1st ed). Nairobi: AMREF GoT (2004): National Infection Prevention and Control (IPC) Guidelines for Healthcare Workers. Dar es Salaam: MOHSW Nordberg, E. (1999): Communicable Diseases, A Manual for Health Workers in Sub-Saharan Africa, Nairobi: AMREF Nordberg, E., Kingondu, T., & Mugambi, E., et al. (2008) Communicable Diseases. (4thed.). Nairobi: AMREF ← Previous TopicNext Topic →View all Disease Control and Prevention topicsOpen Complete Full Notes PDF / OFFLINE NOTES Unataka kutumiwa notes hizi kupitia WhatsApp?Kwa notes zilizopangiliwa vizuri kwa kusoma offline au PDF, bonyeza kitufe hapa chini. Ujumbe wenye Level, Semester, Module na Topic utaandaliwa moja kwa moja.TUMIWA NOTES WHATSAPP WhatsApp: 255620339260

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Bronchitis – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Bronchitis Disease Control and Prevention • Source Session/Topic 18 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 18: Identification of Patients with Bronchitis Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Cause(s) of Bronchitis • Describe Mode of Transmission of Bronchitis • Describe Major Signs and Symptoms of Bronchitis • Explain Treatment of Bronchitis • Explain Prevention and Control of Bronchitis Resources Needed: • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | | 2|05 minutes | |Cause(s) of Bronchitis | | | |Presentation | | |3 |10 minutes |Presentation |Mode of Transmission of Bronchitis | |4 |20 minutes |Presentation |Major Signs and Symptoms of | | | |Buzzing |Bronchitis | |5 |30 minutes |Presentation |Treatment of Bronchitis | | | |Brainstorming | | |6 | 30 |Presentation |Prevention and Control of Bronchitis| | |minutes |Buzzing | | |7 |05 minutes |Presentation |Key Points | |8 |05 minutes |Presentation |Evaluation | |9 |10 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Task (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Bronchitis (5 minutes) Lower respiratory tract infections include infectious processes of the lungs and bronchi, for example, Pneumonia and Bronchitis This session will deal with Bronchitis Bronchitis • Bronchitis refers to an inflammatory condition of the large elements of the trachea-bronchial tree that is usually associated with a generalized respiratory infection • The disease entity is frequently classified as either acute or chronic • Common condition often caused by viral infections of upper respiratory with secondary bacterial infection • Common in children with infectious fever e.g. measles, influenza and whooping cough • It is also common in smokers, the elderly and people with chronic chest disorders Causes • Bacteria: Mycoplasma pneumonia, streptococcal bacteria, haemophillus influenza • Viruses: The common cold viruses, rhinovirus, coronavirus, influenza virus, adenovirus, and respiratory syncytial virus, account for the majority of cases STEP 3: Mode of transmission of Bronchitis (5 minutes) • Usually airborne transmitted from upper respiratory tract infection STEP 4: Signs and Symptoms of Bronchitis (20 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What are the signs and symptoms of Bronchitis? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Cough o Cough is the hallmark of acute bronchitis o Frequently, the cough is initially non-productive but progresses, yielding mucopurulent sputum • Fever with malaise, headache and loss of appetite • Dyspnea • Crepitation in the lungs • Wheezing • The patient typically has nonspecific complaints such as malaise and headache, coryza, and sore throat STEP 5: Treatment of Bronchitis (30 minutes) |Activity: Brainstorming (5 minutes) | | | |ASKstudents to brainstorm on the following question: | | | |What is the treatment of bronchitis? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • Bed rest and mild analgesic-antipyretic therapy are often helpful in relieving the associated lethargy, malaise, and fever • Bronchitis is primarily a self-limiting illness and rarely a cause of death • Patients should be encouraged to drink fluids to prevent dehydration and possibly decrease the viscosity of respiratory secretions • Non-steroidal anti-inflammatory drugs such as aspirin or acetaminophen or ibuprofen is administered every 4 to 6 hours o In children, aspirin should be avoided and acetaminophen used as the preferred agent because of the possible association between aspirin use and the development of Reye’s syndrome • Persistent, mild cough, may be treated with dextromethorphan; o more severe coughs may require intermittent codeine or other similar agents • When possible, antibiotic therapy is directed toward anticipated respiratory pathogen(s) for example penicillin STEP 6: Prevention and Control of Bronchitis (30 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What are the methods for prevention and control of Bronchitis? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • A complete occupational/environmental history for the determination of exposure to noxious, irritating gases, as well as cigarette smoking, must be assessed. • Exposure to bronchial irritants should be reduced. • Attempts should be made with the patient to reduce or eliminate cigarette smoking • Control measures of lower respiratory tract infections are based on general principles governing control of airborne diseases STEP 7: Key Points (5 minutes) • Bronchitis means the bronchial tubes are inflamed and irritated. • Bronchitis is characterized by cough, fever and difficulty in breathing • When antibiotic is needed, penicillins is highly recommended • Control depends on the control of primary diseases • Mortality can be reduced by early diagnosis and treatment STEP 8: Evaluation (5 minutes) • What causes bronchitis? • What is the mode of transmission for common bronchitis? • What are the major signs and symptoms of bronchitis? • What is the treatment of common

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Pneumonia – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Pneumonia Disease Control and Prevention • Source Session/Topic 19 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 19: Identification of Patients with Pneumonia Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe cause of pneumonia, • Describe Mode of Transmission of Pneumonia • Describe Major Signs and Symptoms of Pneumonia • Explain Treatment of Pneumonia • Explain Prevention and Control of Pneumonia Resources Needed: • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | |2 |05 minutes |Presentation |Cause(s) of Pneumonia | |3 |10 minutes |Presentation |Mode of Transmission of Pneumonia | | | |Brainstorming | | |4 |10 minutes |Presentation |Major Signs and Symptoms of | | | |Buzzing |Pneumonia | |5 |20 minutes |Presentation |Treatment of Pneumonia | |6 | 55 |Presentation |Prevention and Control of Pneumonia | | |minutes |Buzzing | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Task (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Pneumonia (5 minutes) Lower respiratory tract infections include infectious processes of the lungs and bronchi, for example pneumonia and bronchitis Pneumonia • Inflammatory condition of the lung caused by infection Causes • Virus • Bacteria: Pneumococci, Streptococci, Staphylococci, Klebsiellae species and Haemophillus influenzae STEP 3: Mode of Transmission of Pneumonia (10 minutes) |Activity: Brainstorming (5 minutes) | | | |ASK students to brainstorm on the following question: | | | |What are the modes of transmission of Pneumonia? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • Airborne from upper respiratory tract infection, especially influenza in the elderly, HIV/AIDS, immunocompromised and measles and whooping cough in children. These infections cause damage to the epithelium of the lungs and so clear the way for bacterial superinfection • Transmission is by droplet spread, direct oral contact or indirectly through freshly infected articles STEP 4: Signs and Symptoms of Pneumonia (10minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What are the signs and symptoms of Pneumonia? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | Signs and Symptoms • Dry or productive Cough • High Fever with malaise, headache and loss of appetite • Chest pain • Dyspnoea (difficult breathing) • Respiratory distress • Crepitation in the lungs • Wheezing STEP 5: Treatment of Pneumonia (20 minutes) • Supportive care: Lower temperature by using analgesics, if wheezing use bronchodilators, daily fluid maintenance(encourage breastfeeding for children) • Medicines o Non-severe pneumonia: Cotrimoxazole, Amoxycillin o Severe pneumonia: Benzyl-penicillin, Chloramphenicol, Gentamycin, Ceftriaxone, Erythromycin and Azithromycin STEP 6: Prevention and Control of Pneumonia (55 minutes) |Activity: Group Discussion (15 minutes) | | | |DIVIDE students into small manageable groups | | | |ASK students to discuss on the following question | | | |What are the prevention and control measures of Pneumonia? | | | |ALLOW students to discuss for 10 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Control measures of lower respiratory tract infections are based on general principles governing control of airborne diseases • Immunisation to prevent diseases complicated by pneumonia such as measles and whooping cough is important • Mortality can be reduced by early diagnosis and treatment especially in children and elderly • Prompt adequate therapy started. STEP 7: Key Points (5 minutes) • Pneumonia is characterized by cough, fever and difficulty in breathing • It occurs as a complication of upper respiratory infections • Treatment will depend if it is a non-severe or severe condition • Control depends on the control of primary diseases and on general principles governing control of airborne diseases • Mortality can be reduced by early diagnosis and treatment STEP 8: Evaluation (5 minutes) • What causes Pneumonia? • What is the mode of transmission for pneumonia? • What are the major signs and symptoms of pneumonia? • What is the treatment of pneumonia? • What are the prevention and control measures of pneumonia? STEP 9: Assignment (5 minutes) |Activity: Take Home Assignment (5 minutes) | | | |DIVIDE individual assignment | | | |ASK the students to work individually on the following Assignment | |Explain preventive measures that you will take to control Pneumonia in | |children and adults | |ALLOCATE time for students to do the assignments and submit | | | |REFER students to recommended reference | References Cook, G.& Zumla, A. (2003). Manson’s Tropical Diseases. (21sted.). London: Saunders Ltd Denyer, S. P. Hodges, N. A. &Gorman, S. P (2011) Ed. Hugo & Russell’s Pharmaceutical Microbiology (8thed). Oxford: Willey-Blackwell publishing Eshuis J, &Manschot,P (1992). Communicable diseases,(1st ed). Nairobi: AMREF GoT (2004): National Infection Prevention and Control (IPC) Guidelines for Healthcare Workers. Dar es Salaam: MOHSW GoT (2013) Standard Treatment Guidelines & National Essential Medicines List (4thed). Dar es Salaam: MOHSW Nordberg, E. (1999): Communicable Diseases, A

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Amoebiasis – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Amoebiasis Disease Control and Prevention • Source Session/Topic 20 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 20: Identification of Patients with Amoebiasis Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Causeof Amoebiasis, • Describe Mode of Transmission of Amoebiasis • Describe Major Signs and Symptoms of Amoebiasis • Explain Treatment of Amoebiasis • Explain Prevention and Control of Amoebiasis Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | |2 |10 minutes |Presentation |Cause(s) of Amoebiasis | |3 |10 minutes |Presentation |Mode of Transmission of Amoebiasis | | | |Brainstorm | | |4 |25 minutes |Presentation |Major Signs and Symptoms of | | | | |Amoebiasis | |5 | 05 |Presentation |Treatment of Amoebiasis | | |minutes | | | |6 |50 minutes |Presentation |Prevention and Control of | | | |Group |Amoebiasis | | | |Discussion | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Amoebiasis (5 minutes) • Amoebiasis: o An infection caused by the amoeba Entamoeba histolytica which is a single-celled organism o E. histolytica is often found in food or water contaminated with human faeces. • The main reservoir of E. histolytica is man • A pathogenic intestinal amoeba is spread between humans by its cysts, characterized by diarrhoea • This infection can be fatal in infant and to older people with low resistance STEP 3: Mode of Transmission of Amoebiasis (10 minutes) |Activity: Brainstorming (5 minutes) | | | |ASKstudents to brainstorm on the following question: | | | |What is the mode of transmission of Amoebiasis? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • The only infective form of E. histolytica is the cyst • It is acquired by ingestion of cysts which is resistant to gastric acid • Cysts are passed from person-to-person by the faecal oral route, by fingers soiled with faeces either directly into the mouth or via food • There have been cases of transmission through sexual contact • The incubation period ranges from two weeks to many years [pic]STEP 4: Signs and Symptoms of Amoebiasis (20 minutes) • Infection with amoebae in most cases is asymptomatic • The presenting features may be gradual, severe or fulminating, and include: o Gradual onset colitis o Severe acute amoebic dysentery Gradual Onset Colitis • Present with: o Mild intermittent diarrhoea o Abdominal discomfort, usually progressing to bloody diarrhoea with mucous. o nausea, o headache o low grade fever o Anorexia Severe Acute Amoebic Dysentery • Amoebic dysentery is a severe form of Amoebiasis • The symptoms of amoebic dysentery include: o Severe diarrhoea that contains blood or mucus o Severe stomach pain o loss of appetite o Loss of weight o Fever o Chills • Occasionally, the infection can spread through the bloodstream to other parts of the body causing an amoebic abscess STEP 5: Treatment of Amoebiasis (10minutes) • Asymptomatic patients normally do not need treatment because in time they clear the infection • Drug of choice: Metronidazole • Alternative drugs of choice: Tinidazole, Secnidazole STEP 6: Prevention and Control of Amoebiasis (50 minutes) |Activity: Group Discussion (15 minutes) | | | |DIVIDE students into small manageable groups | | | |ASK students to discuss on the following question | | | |What are the prevention and control measures of Amoebiasis? | | | |ALLOW students to discuss for 10 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | Prvention and control measures • Early diagnosis and treatment • Food handlers may need to be screened periodically during employment • Drinking water should be boiled to kill the cysts • Proper faecal and refuse disposal • Washing hands after visiting the toilet, before eating and before preparing food • Foods should be well cooked and covered • Health education on how the disease is transmitted • Improvement of living standards • Amoebiasis can be prevented by good hygiene and sanitary conditions • Improve water supply and proper disposal of faeces • Do not eat fresh fruit or vegetables which cannot be peeled before eating • Make sure raw vegetables are washed thoroughly and cooked properly STEP 7: Key Points (5 minutes) • Amoebiasis is an infection caused by potentially pathogenic amoeba E. histolytica • Infection occurs through the faecal-oral transmission route • In severe cases, the onset is more sudden, the patient is ill and toxic with fever and signs of dehydration • Treatment should cover both tissue parasites and parasites in the bowel lumen • Drug of choice for treatment of Amoebiasis is Metronidazole STEP 8: Evaluation (5 minutes) • What is the infective form of entamoeba histolytica? • What are the clinical features of amoebiasis? • What are the drugs used in treatment of amoebiasis? • How can Amoebiasis be prevented and controlled? STEP 9: Assignment (5 minutes) |Activity: Take Home Assignment (5 minutes) | | | |DIVIDE students in groups or individuals | | | |ASK the students to

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Typhoid Fever – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Typhoid Fever Disease Control and Prevention • Source Session/Topic 21 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 21: Identification of Patients with Typhoid Fever Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Cause of Typhoid Fever • Describe Mode of Transmission of Typhoid Fever • Describe Major Signs and Symptoms of Common Typhoid Fever • Explain Treatment of Common Typhoid Fever • Explain Prevention and Control of Typhoid Fever Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | |2 |05 minutes |Presentation |Cause of Typhoid Fever | |3 |20 minutes |Presentation |Mode of Transmission of Typhoid | | | |Brainstorming |Fever | |4 |15 minutes |Presentation |Major Signs and Symptoms of Typhoid| | | | |Fever | |5 |15 minutes |Presentation |Treatment of Typhoid Fever | |6 |35 minutes|Presentation |Prevention and Control of Typhoid | | | |Buzzing |Fever | |7 |05 minutes |Presentation |Key Points | |8 |10 minutes |Presentation |Evaluation | |9 |10 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Typhoid Fever (5 minutes) • Typhoid fever is a systemic infectious disease, caused by bacteria Salmonella typhi and Salmonella paratyphi STEP 3: Mode of Transmission of Typhoid Fever (20 minutes) |Activity: Brainstorming (5 minutes) | | | |Ask students to brainstorm on the following question: | | | |What is the mode of transmission of typhoid fever? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | Mode of transmission • The organisms that are responsible for infection are transmitted through foods or water contaminated with faeces or urine of a patient or carrier • It is more common in areas where there is insufficient water for washing hands • Typhoid is an exclusively human disease • It is transmitted through the ingestion of food or drink contaminated by the faeces or urine of infected people • A person may become an asymptomatic carrier of typhoid fever, suffering no symptoms, but capable of infecting others STEP 4: Signs and Symptoms of Typhoid Fever (15 minutes) • Typhoid fever is characterized by: o Fever as high as 40 °C (104 °F) o Profuse sweating o Drowsiness o Muscle pain o Severe headache o Non-bloody diarrhea although it can sometimes have bloody diarrhea too o The incubation period of typhoid fever varies with the size of the infecting dose, and averages from 10 to 20 days o The onset is gradual STEP 5: Treatment of Typhoid Fever (15 minutes) Drug of choice • Ciprofloxacin o Contraindication : Pregnancy and Children below 15 years Alternatively • Chloramphenicol o Contraindication: Third trimester of pregnancy STEP 6: Prevention and Control of Typhoid Fever (35 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What are the measures for prevention and control of Typhoid? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | Measures of prevention and control • Early diagnosis and treatment of cases is important • General prevention is as for faecal-oral diseases: o Cook food thoroughly o Boil drinking water o Wash hands before preparing food, after preparing food and before eating • It is important to identify carriers who work as food handlers as they are especially likely to transmit the infection (although searching for carriers is impracticable in endemic areas) • Immunization STEP 7: Key Points (5 minutes) • Typhoid fever is a systemic bacterial infection caused by Salmonella typhi, in areas where sanitation is poor • Drug of choice for treatment of typhoid fever is ciprofloxacin • Delayed treatment may lead the severe complications such as bleeding from bowel, bowel perforation and peritonitis • Safe water, supply and food hygiene will prevent the population from infection STEP 8: Evaluation (10 minutes) • What is the cause of typhoid fever? • What is the mode of transmission of typhoid fever? • What are signs and symptoms of typhoid fever? • What is the treatment of typhoid fever? • How is typhoid fever prevented? STEP 9: Assignment (5 minutes) | Activity: Take Home Assignment (5 minutes) | | | |DIVIDE students in groups or individual assignment | | | |ASK the students to work individually on the following Assignment | |Prepare a presentation explaining how to differentiate a patient | |suffering Typhoid fever from the one having Amoebiasis | |ALLOCATE time for students to do the assignments and submit | | | |REFER students to recommended references | References Cook, G. Zumla, A. (2003). Manson’s Tropical Diseases. (21sted.). London: Saunders Ltd Denyer, S. P. Hodges, N. A. Gorman, S. P (2011) Ed. Hugo & Russell’s Pharmaceutical Microbiology (8thed). Oxford: Willey-Blackwell publishing Eshuis, J, Manschot, P (1992). Communicable diseases,(1st ed). Nairobi: AMREF GoT (2013) Standard Treatment Guidelines & National Essential Medicines List (4thed). Dar es Salaam: MOHSW GoT (2004): National Infection Prevention and Control (IPC) Guidelines for Healthcare Workers. Dar es Salaam: MOHSW Nordberg, E. (1999): Communicable Diseases, A Manual for Health Workers in Sub-Saharan Africa, Nairobi: AMREF Nordberg, E.,

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Food Poisoning – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Food Poisoning Disease Control and Prevention • Source Session/Topic 22 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 22: Identification of Patients with Food Poisoning Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Cause of Food Poisoning • Describe Mode of Transmission of Food Poisoning • Describe Major Signs and Symptoms of Food Poisoning • Explain Treatment of Food Poisoning • Explain Prevention and Control of Food Poisoning Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |15 minutes |Presentation |Cause of Food Poisoning | | | |Buzzing | | |3 |15 minutes |Presentation |Mode of Transmission of Food | | | |Brainstorming |Poisoning | |4 |15 minutes |Presentation |Major Signs and Symptoms of Food | | | | |Poisoning | |5 |15 minutes |Presentation |Treatment of Food Poisoning | |6 |40 minutes |Presentation |Prevention and Control of Food | | | |Small group |Poisoning | | | |Discussion | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Food Poisoning (15 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What causes food poisoning? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | Definition Food poisoning is an acute intestinal disease acquired by consumption of contaminated food or water Causes Food poisoning can be divided into two categories: • Chemical (heavy metals, fluoride and others) • Infectious: Toxins produced by microorganism present in natural food or bacteria contaminating food or water o Infectious agents include viruses, bacteria, and parasites o Toxic agents include poisonous mushrooms, improperly prepared exotic foods Bacteria • Bacteria can cause food poisoning in two different ways o Some bacteria infect the intestines, causing inflammation and difficulty absorbing nutrients and water, leading to diarrhoea o Other bacteria produce chemicals in foods (known as toxins) that are poisonous to the human digestive system ▪ When eaten, these bacterial toxins can lead to nausea, vomiting, kidney failure, and even death • The common bacteria causing food poisoning are: ▪ Salmonellae, ▪ Campylobacter, ▪ Staphylococcus aureus ▪ Escherichia coli ▪ Clostridium botulinum ▪ Vibrio cholerae Pesticides • In food and naturally toxic substances like poisonous mushrooms or reef fish Viruses • These viruses include: o Noroviruses o Rotavirus o Enteroviruses o Hepatitis A Parasites • They are usually in contaminated or untreated water and cause long- lasting but mild symptoms o Examples of parasites which can cause illness are Giardia and Cryptosporidium Note: Toxic agents are the least common cause of food poisoning STEP 3: Mode of Transmission of Food Poisoning (15 minutes) |Activity: Brainstorming (15 minutes) | | | |ASK students to brainstorm on the following question: | | | |How is food poisoning transmitted? | | | |ALLOW few students to respond | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • Illness is often isolated episode caused by poor food preparation or selection o Eating wild toxic mushrooms, o Eating fish and other seafood that contains toxins o Eating food which has been contaminated with pesticides • Food poisoning illness usually arises from improper handling, preparation, or food storage • The illness is transmitted by undercooked foods such as eggs, potato, salads poultry, raw milk, dairy products, fish and other sea foods STEP 4: Signs and Symptoms of Food Poisoning (15 minutes) • Symptoms of food poisoning depend on the type of contaminant and the amount eaten • The symptoms can develop rapidly, within 30 minutes, or slowly, worsening over days to weeks • Most of the common signs and symptoms are: o Nausea, o Vomiting o Diarrhoea o Abdominal cramping • The incubation period is short depending on the cause of food poisoning: o Staphylococcal food poisoning takes 1 – 6 hours o Salmonella food poisoning takes 12 – 14 hours o Anthrax gastrointestinal poisoning take 2 – 5 days • There is acute onset of vomiting and diarrhoea after ingestion of contaminated food • Gastrointestinal anthrax presents with vomiting, abdominal pain, haematemesis, bloody diarrhoea and toxaemia • Staphylococcus aureus: Causes moderate to severe illness with rapid onset of nausea, severe vomiting, dizziness, and abdominal cramping • Clostridium botulinum (botulism): Causes severe illness affecting the nervous system o Symptoms start as blurred vision o The person then develops problems of talking and overall weakness o Symptoms then progress to difficulty breathing and inability to move arms or legs o Botulism has the 4 D’s: diplopia (double vision), dysphagia (difficulty swallowing), dysarthria/dysphonia (difficulty speaking) and diarrhoea • Neurological symptoms suggest insecticides e.g. organophosphorous or mushroom poisoning and seafood poisoning STEP 5: Treatment of Food Poisoning (15 minutes) • Symptomatic treatment to correct dehydration by ORS or intravenous fluid. o Helps to correct electrolyte imbalance that might arise from diarrhoea and vomiting o The patient may need to be admitted to the hospital ▪ This depends on the severity of the dehydration, response to therapy, and ability to drink

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Cholera – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Cholera Disease Control and Prevention • Source Session/Topic 23 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 23: Identification of Patients with Cholera Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Cause of Cholera • Describe Mode of Transmission of Cholera • Describe major Signs and Symptoms of Cholera • Explain Treatment of Common Cholera • Explain Prevention and Control of Cholera Resources Needed • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |10 minutes |Presentation |Causes of Cholera | | | |Buzzing | | |3 |40 minutes |Presentation |Mode of Transmission of Cholera | | | |Small group | | | | |Discussion | | |4 |10 minutes |Presentation |Major Signs and Symptoms of Cholera | | | |Brainstorming | | |5 |10 minutes |Presentation |Treatment of Cholera | |6 |30 minutes |Presentation |Prevention and Control of Cholera | | | |Small group | | | | |Discussion | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Cholera (10 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What causes cholera? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | Definition • Cholera is acute diarrheal infection of the intestine caused by vibrio cholerae • The infection is often mild or without symptoms, but sometimes can be severe and fatal STEP 3: Mode of Transmission of Cholera (40 minutes) |Activity: Group discussion (30 minutes) | | | |DIVIDEstudents into small manageable groups | | | |ASK students to discuss on the following question | | | |How is cholera transmitted? | | | |ALLOW students to discuss for 15 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Transmission is through faecal –oral route but almost all cholera infections are water- borne (see figure 1). o Vibrio cholera can live in water for 2 weeks and prefer salty water o Vibrio may survive for longer period and multiply in shellfish The reservoir of infection is formed mainly by carriers excrete vibrio in small numbers posing danger to the community [pic] STEP 4: Signs and Symptoms of Cholera (10 minutes) |Activity: Brainstorming (15 minutes) | | | |Ask students to brainstorm on the following question: | | | |What are the signs and symptoms of cholera? | | | |ALLOW few students to respond? | | | |WRITE their responses on the flip chart/ board | | | |CLARIFY and SUMMARISE by using the content below | • The incubation period is 2-3 days • The clinical presentation of cholera is caused by water and electrolyte loss and develop in 3 stages described below: First stage (last for 3-12 hours) • Characterized by passage of profuse watery stool • The stool comprises of clear fluid with flakes of mucous (rice water appearance) • vomiting • Severe cramps in the abdomen and limbs develop from loss of electrolytes Second stage: • There is collapse from dehydration • The body becomes cold, the skin dry and inelastic • The blood pressure is low and the pulse is rapid and feeble • Urine production stops and the patient may die of shock Third stage: • Stage of recovery, either spontaneously or with treatment • Diarrhoea decreases • Patient is able to take fluids and general condition improves STEP 5: Treatment of Cholera (10 minutes) • Patients should be hospitalised Rehydration • Cholera is cured by appropriate and timely rehydration o Patients of all ages who are strong enough to drink will take a lot of glucose/electrolyte solution needed for rehydration and maintenance • It is essential to use oral rehydration solution (ORS) or appropriate intravenous (IV) fluids to replace the necessary electrolytes. • Patients in shock or who are too weak to drink require intravenous fluids until they can take in oral fluids. Antimicrobials • Antimicrobial agents have been shown to shorten the period of diarrhoea and the amount of fluid loss o Tetracycline or doxycycline are the drugs of choice o Erythromycin is an effective alternative both in children and adults o Cotrimoxazole is also another alternative • Strict isolation is not necessary as only vomitus and stool are infectious • Patients are treated on ‘Cholera bed’ (beds with central hole) through which the continuous stool can pass into a bucket and fluid loss be measured [pic] STEP 6: Prevention and Control of Cholera (30minutes) |Activity: Group discussion (30 minutes) | | | |DIVIDEstudents into small manageable groups | | | |ASK students to discuss on the following question | | | |What are the prevention and control measures of cholera? | | | |ALLOW students to discuss for 15 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board |

Pharmaceutical Sciences Notes, PST Level 4 Semester 1, PST NTA Level 4, PST04102 Disease Control and Prevention

Identification of Patients with Ascariasis – PST04102 Disease Control and Prevention

NTA Level 4 • Semester 1 • PST04102 Identification of Patients with Ascariasis Disease Control and Prevention • Source Session/Topic 24 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 24: Identification of Patients with Ascariasis Total Session Time: 120 minutes + 2 hours Assignment Prerequisites • None Learning Tasks By the end of this session students are expected to be able to: • Describe Causes of Ascariasis • Describe Mode of Transmission of Ascariasis • Describe Major Signs and Symptoms of Ascariasis • Explain Treatment of Ascariasis • Explain Prevention and Control of Ascariasis Resources Needed: • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Computer and LCD Projector SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |5 minutes |Presentation |Introduction, Learning Tasks | |2 |10 minutes |Presentation |Cause(s) of Ascariasis | | | |Buzzing | | |3 |30 minutes |Presentation |Mode of Transmission of Ascariasis| | | |Small group | | | | |Discussion | | |4 |10 minutes |Presentation |Major Signs and Symptoms of | | | | |Ascariasis | |5 |10 minutes |Presentation |Treatment of Ascariasis | |6 |40 minutes |Presentation |Prevention and Control of | | | |Small group |Ascariasis | | | |Discussion | | |7 |5 minutes |Presentation |Key Points | |8 |5 minutes |Presentation |Evaluation | |9 |5 minutes |Presentation |Assignment | SESSION CONTENTS STEP1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASKstudents to read the learning tasks and clarify ASK students if they have any questions before continuing STEP 2: Causes of Ascariasis (10 minutes) |Activity: Buzzing (10 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |What causes Ascariasis? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Ascariasis: is one of the commonest infections of the small intestine • Caused by a nematode called Ascaris lumbricoides ( round worm) STEP 3: Mode of Transmission of Ascariasis (30 minutes) |Activity: Group discussion (30 minutes) | | | |DIVIDEstudents into small manageable groups | | | |ASK students to discuss on the following question | | | |What is the mode of transmission of Ascariasis? | | | |ALLOW students to discuss for 15 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Common ways of acquiring Ascariasis include failure to adhere to hygienic practices such as washing hands before food preparation and proper storage of food • Therefore the disease is related to poor sanitation and hygiene • Infection is acquired from ingestion of food contaminated with mature eggs • The usual vehicles are fruits and other raw food • Children are more frequently infected and have higher worm burden than adults because they like putting contaminated objects into their mouths • Heavy infection in children can contribute to under-nutrition • Adults have much lighter infections, although re-infection can occur throughout life [pic][pic]Refer students to Handout 24:1 Life cycle of ascaris lumbricoides for further reading STEP 4: Signs and Symptoms of Ascariasis (10 minutes) • Fever • Cough • Abdominal discomfort, restlessness and insomnia (sleeplessness) • Eosinophilia due to allergic reaction • Intestinal obstruction • Passing adult worm in the stool or vomitus • Obstructive jaundice STEP 5: Treatment of Ascariasis (10 minutes) • Treatment is effective only against the adult worms • The drugs of choice are as follows: o Albendazole: for children 2-5 years a single dose of 200mg and for older children and adults, one dose of 400mg is given o Mebendazole: a single dose 500mg o Levamisole: a single of 2.5mg/kg body weight o Piperazine (antepar): syrup at a dose of 150mg/kg body weight (to a maximum of 4g) as a single dose ▪ Note that these drugs are given between meals ▪ They should be avoided during the first tree monthsr of pregnancy STEP 6: Prevention and Control of Ascariasis (40 minutes) |Activity: Group discussion (30 minutes) | | | |DIVIDEstudents into small manageable groups | | | |ASK students to discuss on the following question | | | |How is Ascariasis transmitted? | | | |ALLOW students to discuss for 15 minutes | | | |ALLOW few groups to present and the rest to add points not mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Environmental measures such as provision of adequate and safe water supplies. • Proper disposal of faeces • prevention of faecal contamination of food and water • Discourage use of fresh human faeces as manure • Health education on: o Proper use of latrines o Personal hygiene e.g. washing hands after using toilet or before handling food o Washing fruits and vegetables before eating o Use of dry racks for utensils so that they are above the soil and dust STEP 7: Key Points (5 minutes) • Ascariasis is a common nematode infection. • The prevalence of Ascariasis is related to poor sanitation and hygiene • Control is mainly by improving faeces disposal • A heavy infection in a child can contribute to malnutrition STEP 8: Evaluation (5 minutes) • What is Ascariasis? • How does a person acquire Ascariasis infection? • What are the signs and symptoms of Ascariasis? • What is the treatment of Ascariasis? • What are preventive and control measures of Ascariasis? STEP 9: Assignment (5 minutes) |Activity: Take Home Assignment (10 minutes) | | | |DIVIDE

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