Adverse Drug Reactions, Drug Overdose and Intoxication – PST04101 Dispensing
NTA Level 4 • Semester 1 • PST04101 Adverse Drug Reactions, Drug Overdose and Intoxication Dispensing • Source Session/Topic 13 Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability. Session 13: Adverse Drug Reactions, Drug Overdose and Intoxication Total Session Time: 120 minutes Prerequisites • None Students Learning Tasks By the end of this session students are expected to be able to: • Define ADRs, Drug Overdose and Intoxication • Identify suspected adverse drug reactions (ADRs), drug overdose and intoxication • Report suspected adverse drug reactions (ADRs) Resources Needed: • Flip charts, marker pens, and masking tape • Black/white board, chalk and whiteboard markers • Handout 13.1 Adverse Drug Reactions Cases • Worksheet 13.1 TFDA ADR form SESSION OVERVIEW |Step |Time |Activity/ |Content | | | |Method | | |1 |05 minutes |Presentation |Introduction, Learning Tasks | |2 |05 minutes |Presentation |Definition of Adverse Drug | | | | |Reactions, Drug Overdose and | | | | |Intoxication | |3 |35 minutes |Presentation |Identification of Adverse Drug | | | |Brainstorming |Reactions (ADRs), Drug Overdose and | | | | |Intoxication | |4 |60 minutes |Presentation |Reporting Adverse Drug Reactions | | | |Small Group |(ADRs) | | | |Discussion | | |5 |10 minutes |Presentation |Key Points | |6 |05 minutes |Presentation |Evaluation | SESSION CONTENTS STEP 1: Presentation of Session Title and Learning Tasks (5 minutes) READ or ASK students to read the learning tasks and clarify ASK students if they have any questions before continuing. STEP 2: Definition of Adverse Drug Reactions (5 minutes) • Adverse Reaction is a situation where someone experiences harmful effects from the application of a drug or is an unfavourable or harmful unintended action of a medicine • Serious adverse drug reaction: any reaction that is fatal, life- threatening, permanently/significantly disabling, requires or prolongs hospitalization, causes a congenital anomaly, or requires intervention to prevent permanent impairment or damage • Drug Overdose describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced ▪ An overdose may result in a toxic state or death • Combined drug intoxication (CDI), also known as multiple drug intake (MDI) or lethal polydrug/polypharmacy intoxication is due to the simultaneous use of multiple drugs, whether the drugs are prescription, over-the-counter, recreational, or some other combination STEP 3: Identification of Adverse Drug Reactions (ADRs) (35 minutes) |Activity: Buzzing (5 minutes) | | | |ASK students to pair up and buzz on the following question for 2 | |minutes | | | |How will one identify Adverse Drug Reactions? | | | |ALLOW few pairs to respond and let other pairs to add on points not | |mentioned | | | |WRITE their response on the flip chart/board | | | |CLARIFY and SUMMARIZE by using the content below | • Patients may experience one or more adverse reactions when they are given medicines Adverse reactions (Side effect) are undesirable drug effects which may be common or may occur infrequently • They may be mild, severe, or life-threatening. They may occur after the first dose, after several doses, or even after many doses • An adverse reaction often is unpredictable, although some drugs are known to be cause certain adverse reactions in many patients • For example the drugs used in the treatment of Cancer and those used in treating HIV/AIDS, commonly known as Anti-Retralviral Therapy(ART) are very toxic and are known to produce adverse reactions in many patients receiving them • Other medicines produce adverse reactions in fewer patients • Some adverse reactions are predictable, but many adverse drug reactions occur without warning • When dealing/ dispensing medicines that are suspected to have ADRs: o Counsel all patients regarding the possibility of ADRs o Inform patients of signs and symptoms that may indicate an ADR o Instruct patients that in the event of an ADR, they should return to the clinic/hospital immediately if the reaction is life-threatening or contact the MO as soon as possible in all other instances o Refer all patients with suspected ADRs to the MO o After a period to be determined by the ART Eligibility Committee, complete one ADR form for each ADR reported ▪ Refer patients with suspected serious ADRs or patients requiring treatment to the MO o Work with the Records Officer and the nursing staff to make sure that the original ADR form is placed in the patient record and the duplicate is received by the pharmacist o Maintain a file of all completed ADR forms and related reports o Review ADR forms on an ongoing basis and alert the ART Eligibility Committee of unusual trends or findings o Provide verbal feedback at ART Eligibility Committee meetings, or written feedback to staff regarding outcomes of referred ADRs so as to encourage continued reporting o Prepare ADR Summary Report o Present the ADR Summary Report and findings to the ART Eligibility Committee • Signs and symptoms of drug overdose vary depending on the drug or toxin exposure o The substance that has been taken may often be determined by asking the person o For patients with altered level of consciousness, questioning of their friends and family may be helpful in order to get information of the drug involved [pic][pic] Refer students to Worksheet 13.1: TFDA ADR FORM STEP 4: Reporting Adverse Drug Reactions (ADRs) (60 minutes) |Activity: Small Group Discussion (30minutes) | | | |DIVIDE students into small manageable groups. | | | |[pic]REFER students to Worksheet 12.1: TFDA ADR FORM | | | |READ the form and CLARIFY | | | |ASK all groups to discuss about the following question for 15 minutes.| | | |Where to report in case of ADR? | |What to report on ADR form? | |Who should report? | |How to report? | | | |ALLOW few groups to present and the rest to add points not mentioned