Pharmacotherapy of Tracheobronchitis in Dogs – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Tracheobronchitis in Dogs

Basic Veterinary Pharmacology • Source Session/Topic 36
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PST 06107

Basic Veterinary Pharmacology

Session 36: Pharmacotherapy of Tracheobronchitis in Dogs

Learning Tasks

By

the end of this session students are expected to be able to:

Define tracheobronchitis in dogs

List signs and symptoms of tracheobronchitis in dogs

Describe pharmacological treatment of tracheobronchitis in dogs

Describe control and prevention of tracheobronchitis in dogs

Activity: Buzzing

What

is Tracheobronchitis in

dogs?

Definition of Tracheobronchitis in Dogs

Infectious tracheobronchitis (Kernel cough) is a self-limiting mild disease of dogs that results from inflammation of the upper airways

The disease may progress to fatal bronchopneumonia in puppies or to chronic bronchitis in debilitated adult or aged dogs

The illness spreads rapidly among susceptible dogs housed in close confinement

Infections involved include Canine parainfluenza virus, canine adenovirus 2 (CAV-2), or canine distemper virus, can be the primary or sole pathogen involved

Definition of Tracheobronchitis in Dogs

Cont.…

Secondary infection may be caused by

Bordetella

bronchiseptica

especially in dogs of less than 6 months old

Other bacteria such as

Pseudomonas

sp

,

Escherichia

coli

, and

Klebsiella

pneumoniae

may also cause secondary infections after viral injury to the respiratory tract

Stress and extremes of ventilation, temperature, and humidity apparently increase susceptibility to, and severity of, the disease

Signs and Symptoms of Tracheobronchitis in Dogs

Paroxysms

of a harsh dry and easily induced cough, followed by retching and gagging to more severe signs such as fever, purulent nasal discharge, depression, anorexia, and a productive cough, especially in puppies indicates a complicating systemic infection such as distemper or bronchopneumonia.

Disease relapses after stress, particularly due to adverse environmental conditions and improper

nutrition

Severity diminishes during the first 5 days, but the disease persists for 10-20 days

Pharmacological Treatment of Tracheobronchitis in Dogs

Codeine

phosphate 0.25 mg/kg, q 6-12 h, PO to control persistent nonproductive coughing

In severe chronic cases:

Tetracycline 10-22 mg/kg, PO, q 8 h for 5 days, or

Sulfamethazine

-Trimethoprim (200:40mg) 5- 30 mg/kg, IM, q 24 h, for 3-5days, or
Chloramphenicol, 30-50 mg/kg, IM, IV or PO q 8

hr

for 3-5 days

In more severe cases:

Gentamicin sulfate (50 mg) diluted in 3 mL of saline may be administered by

aerosolization

q 12 h for 3 days, plus

Phenylbutazone

20gm in 100ml, 1ml/15kg IM, q 24 h for 1-4 days

Activity:

Brainstorming

• What

are the preventive and control measures for Tracheobronchitis in Dogs?

Prevention and Control of Tracheobronchitis in Dogs

Immunization

with modified live virus vaccines against

distempe

Key Points

Infectious

tracheobronchitis is a self-limiting mild disease of dogs that results from inflammation of the upper airways

Symptoms and signs include paroxysms of a harsh dry and easily induced cough, followed by retching and gagging

Evaluation

What

is Tracheobronchitis in dogs?

What are the common signs and symptoms of Tracheobronchitis in dogs?

What is the pharmacological treatment of Tracheobronchitis in dogs?

What are the control measures against Tracheobronchitis in dogs?

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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