Pharmacotherapy of Tuberculosis and Ectoparasite Infections in Poultry – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Tuberculosis and Ectoparasite Infections in Poultry

Basic Veterinary Pharmacology • Source Session/Topic 30
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PST 06107

Basic Veterinary Pharmacology

Session 30: Pharmacotherapy of Tuberculosis and

Ectoparasites

Infections in

Poultry

Learning Tasks

By

the end of this session students are expected to be able to:

Define Tuberculosis and

Ectoparasites

in Poultry

List signs and symptoms of Tuberculosis and

Ectoparasites

in Poultry

Describe pharmacological treatment of Tuberculosis and

Ectoparasites

in Poultry

Describe Control and Prevention of Tuberculosis and

Ectoparasites

in Poultry

Activity: Buzzing

• What

is Tuberculosis in Poultry?

Definition of Tuberculosis in Poultry

Tuberculosis is a slowly spreading, chronic, granulomatous bacterial infection, characterized by gradual weight loss

Mycobacterium

avium

serovars

1 and 2 are the usual causes

Infected birds excrete the organism in their feces

Cadavers and offal may infect predators and cannibalistic

flockmates

Signs and Symptoms of Tuberculosis in Poultry

Signs

usually develop late in the infection when birds become thin and sluggish, and lameness may be seen

In chickens, granulomatous nodules of varying size are usually found in the liver, spleen, bone marrow, and intestine

Pharmacological Treatment of Tuberculosis in Poultry

Antituberculosis

drugs are not often used to treat chicken.

Isoniazid 30 mg/kg plus

Ethambutol

30 mg/kg plus rifampin 45 mg/kg, PO, for 18 months are effective for the treatment of exotic birds

Activity:

Brainstorming

What

are the prevention and control measures against Tuberculosis in Poultry??

Prevention and Control of Tuberculosis in Poultry

Depopulation

and good biosecurity practices including rodent control and screening

Addition of exotic birds to an exhibit should originate from a closed collection with no history of tuberculosis,

ie

, tuberculosis has not been reported previously or diagnosed on necropsy during the past 5 years

If no history is available, the birds should be quarantined or maintained in a separate exhibit away from the bird

aviary

Prevention and Control of Tuberculosis in Poultry

Cont.….

Therefore, it is recommended that endangered and valuable species be housed in individual exhibits to prevent transmission which is through ingestion of food or water contaminated with

M.

avium

ss

,

i.e

,

feces

from contagious birds

Infected poultry should be destroyed, and housing facilities thoroughly cleaned and disinfected using cresylic compounds

Key Points

Avian

tuberculosis is a chronic infectious disease characterized by the formation of granulomatous lesions in viscera, a progressive weight loss and death

The aetiological agent is Mycobacterium

avium

, a very resilient and acid-resistant

micro¬organism

Improved general sanitation has largely eliminated this infection

Evaluation

What

is Tuberculosis in Poultry?

What are the common signs and symptoms of Tuberculosis in Poultry?

What is the pharmacological treatment of Tuberculosis in Poultry?

What are the control measures against Tuberculosis in Poultry?

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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