Pharmacotherapy of Chronic Respiratory Disease in Poultry – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Chronic Respiratory Disease in Poultry

Basic Veterinary Pharmacology • Source Session/Topic 18
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PST 06107

Basic Veterinary Pharmacology

Session 18: Pharmacotherapy of Chronic Respiratory Disease in Poultry

Learning Tasks

By

the end of this session students are expected to be able to:

Define Chronic Respiratory Disease in Poultry

List signs and symptoms of Chronic Respiratory Disease in Poultry

Describe pharmacological treatment of Chronic Respiratory Disease in Poultry

Describe Control and Prevention of Chronic Respiratory Disease in Poultry

Activity: Buzzing

What

is Chronic Respiratory Disease in

Poultry?

Definition of Chronic Respiratory Disease in Poultry

Chronic Respiratory Disease (CRD) also called

air sacculitis

is an infection of chicken and turkeys caused by

Mycoplasma

gallisepticum

.

The disease is transmitted in eggs or by indirect contact

The disease is characterized by respiratory signs and lesions.

Once started it follows a prolonged course in a flock.

Concurrent

infections such as infectious bronchitis virus, Newcastle disease virus,

Escherichia coli

,

Pasteurella

multocida

and

Haemophilus

paragallinarum

or increased level of dust in the environment predispose to CRD.

Signs

and Symptoms of Chronic Respiratory Disease in Poultry

Signs

of CRD in a flock develop slowly and are usually manifested by drop in egg and meat production.

They show varying degrees of respiratory distress, with slight to marked

rales

, difficulty in breathing, coughing, and/or sneezing.

The lesions include

airsacculitis

,

fibrinous

perihepatitis

and adhesive pericarditis

.

Chickens Infected with MG Have Nasal and Eye Discharges

Pharmacological

treatment of Chronic Respiratory Disease in Poultry

Tetracycline

2.5 to 10 mg/kg, PO in drinking water q 24 h for 3-5days, or

Tiamulin 10%, 1:300-600 diluted in drinking water for 5 days, or

Erythromycin 1: 10000 liters of drinking water for 3 days, or

Tylosin, 0.5% in drinking water, or

Enrofloxacin 15 mg/kg, IM, q12h or other fluoroquinolones can be given in the feed or water for 5-7 days; however, relapses are common

Activity:

Brainstorming

What

are the prevention measures for Chronic Respiratory Disease??

Prevention

and Control of Chronic Respiratory Disease in Poultry

Control

and Prophylaxis

Improve the management, husbandry or nutrition

reduce dust in the house

remove

accumulated litter

I

mprove

ventilation

Evaluation

What

is Chronic Respiratory Disease?

What are the common signs and symptoms Chronic Respiratory Disease?

What is the pharmacological treatment of Chronic Respiratory Disease?

What are the control measures against Chronic Respiratory Disease

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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