Calculations of Percentage Strength (mg %W/V, mg%W/W) – PST04105 Pharmaceutical Calculations

NTA Level 4 • Semester 1 • PST04105

Calculations of Percentage Strength (mg %W/V, mg%W/W)

Pharmaceutical Calculations • Source Session/Topic 15
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.
Session 15: Calculations of Percentage Strength (mg %W/V, mg%W/W)

Total Session Time: 120 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• Calculating the amount of a product/active ingredient from a given
percentage mg% w/v
• Calculating the amount of a product/active ingredient from a given
percentage mg% w/w

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers

SESSION OVERVIEW

|Step |Time |Activity/ |Content |

| | |Method | |

|1 |05 minutes |Presentation |Introduction, Learning Tasks |

|2 |50 minutes |Presentation |Amount of aProduct/Active Ingredient|

| | | |From a Given Percentage Mg %W/V |

|3 |50 minutes |Presentation |Amount of aProduct/Active Ingredient|

| | |Group |From a Given Percentage Mg %W/W |

| | |discussion | |

|4 |05 minutes |Presentation |Key Points |

| 5 |10 minutes |Presentation |Evaluation |

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing.

STEP 2: Amount of a Product/Active Ingredient From a Given Percentage Mg

%W/V (50 minutes)

• The term milligrams percent w/v (mg %w/v) expresses the number of

milligrams of a substance in 100mL of a liquid

• It is used to frequently to donate the concentration of a drug or natural

substances in a biological fluid, as in the blood.

o For example: 30mg% non protein nitrogen, means that each 100 mL
of blood contains 30 mg of non protein nitrogen

|Activity: Small Group Discussion (20 minutes) |

| |

|DIVIDE students into small manageable groups |

| |

|ASK students to discuss on the following question |

|Calculate the amount of drug required to prepare 500 mL of 1000 mg% w/v|

|solution? |

| |

|ALLOW students to discuss for 15 minutes |

| |

|ALLOW few groups to present and the rest to add points not mentioned |

| |

|CLARIFY and SUMMARIZE by using the contents below |

• The following is the answer for the above exercise:

The amount of drug will be calculated as

1000mg = 100ml
Xmg = 500ml
X = 1000mg x 500ml/100ml
X = 5000mg
X =5000mg, answer

STEP 3: Amount of a Product/Active Ingredient From a Given Percentage Mg

%W/W (50 minutes)

• The term milligrams percent w/w (mg %w/w) expresses the number of

milligrams of a substance in 100 gm of a product

o For example: 500mg%w/w benzoic acid ointment, means that each 100
gm of the ointment it contains 500 mg of benzoic acid

|Activity: Small Group Discussion ( 20 minutes) |

| |

|DIVIDE students into small manageable groups |

| |

|ASK students to discuss on the following question |

|Calculate the amount of phenol which should be used to prepare 240gm of|

|5000 mg% w/w solution? |

| |

|ALLOW students to discuss for 15 minutes |

| |

|ALLOW few groups to present and the rest to add points not mentioned |

| |

|CLARIFY and SUMMARIZE by using the contents below |

• The following is the answer for the above exercise:

The amount of drug will be calculated as

5000mg = 100mg
Xmg = 240mg
Xmg = 5000mg x 240mg/100mg
X = 12,000mg, answer

STEP 4: Key Points (5 minutes)

• The term milligrams percent w/v (mg %w/v) expresses the number of

milligrams of a substance in 100mL of a liquid

• It is used to frequently to donate the concentration of a drug or natural

substances in a biological fluid, as in the blood

STEP 5: Evaluation (10 minutes)

• What is the meaning of mg%w/v?
• What do you understand by 400mg%w/v dextrose solution?

References

Ansel, H. C & Stocklosa, M. J. (2001). Pharmaceutical Calculations (11th

ed.). Philadelphia, United States: LIPPINCOTT WILLIAMS & WILKINS

Ansel, H. C (2010) Pharmaceutical Calculations (13rd ed.). Philadelphia,

United States: LIPPINCOTT WILLIAMS & WILKINS

Senya, S. S, Mwasha, C.Y, Muyinga, A. M, Amiri,R. I. and Mauga E.A.S.K.

(2011) Tanzania Pharmaceutical Handbook (2nd ed.). Dar eS Salaam,

Tanzania: School of Pharmaceutical Sciences.

Zatz, J.L and Teixeira, M.G. (2005). Pharmaceutical Calculation (4th ed.).

New Jersey: John Wiley & Sons, Inc

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