Pharmacotherapy of African Swine Fever
PST 06107
Basic Veterinary Pharmacology
Session 31: Pharmacotherapy
of
African Swine Fever
Learning Tasks
By
the end of this session students are expected to be able to:
Define
African
swine fever
List signs and symptoms of
African
swine fever
Describe pharmacological treatment of
African
swine fever
Describe control and prevention of
African
swine fever
Activity: Buzzing
is African swine fever?
Definition of African Swine Fever
It is a peracute highly contagious and highly fatal disease of pig caused by African swine fever virus
The transmission occurs by Argaside ticks
Once established, the disease spread rapidly by direct contact or ingestion of contaminated feed
Signs and Symptoms of African Swine Fever
Fever
that subside after four days
Development of cyanotic skin
Anorexia
Huddling together
Disinclination to move
Incoordination of hind quarter
Moving using front legs dragging the hind legs
Naso-occular
discharge
Dyspnea and cough
Pharmacological Treatment of African Swine Fever
No
specific treatment but treat with antibiotics for secondary bacterial infection.
Lincomycin
Oxytetracycline
Trimethoprim-
sulphadiazine
Activity:
Brainstorming
What
are the prevention and control measures for
African
swine fever?
Prevention and Control of African Swine Fever
Maintain
disease free status by restriction of pig movement and serological monitoring and prevention of contact between domestic pigs and warthogs
Prohibition of importation of pigs and pig products
Currently there is no approved vaccine for
ASF
Prevention and Control of African Swine Fever
Cont.…
Prevention depends on implementation of appropriate import policies and biosecurity measures, ensuring that neither infected live pigs nor pork products are introduced into areas free of ASF.
This includes ensuring proper disposal of waste food from aircraft, ships or vehicles coming from affected countries and policing illegal imports of live pigs and pork products from affected countries
Key Points
African
swine fever (ASF) is a highly contagious haemorrhagic viral disease of domestic and wild pigs, which is responsible for serious economic and production losses.
It is caused by a large DNA virus of the
Asfarviridae
family, which also infects ticks of the genus
Ornithodoros
Clinical signs and mortality rates can vary according to the virulence of the virus and the type/species of pig
Prevention depends on implementation of appropriate import policies and biosecurity measures, ensuring that neither infected live pigs nor pork products are introduced into areas free of ASF
Evaluation
What
is African swine fever?
What are the common signs and symptoms of African swine fever?
What is the pharmacological treatment of African swine fever?
What are the control measures against African swine fever?
References
Riviere
J. E.,
Papich
M. G. (2009).
Veterinary Pharmacology and Therapeutics
(9
th
Ed) Iowa, Wiley-
Blackwel
Publishers
Hsu
W. H. (2008).
Handbook of Veterinary Pharmacology
(1
st
Ed) Iowa, Wiley-
Blackwel
Publishers
Kuafmann
J, (1996).
Parasitic infections of domestic animals
, (2
nd
ed
).Berlin,
Birkhäuser
Verlag
Press
Hoare
E. W. (2013).
A manual veterinary therapeutics & pharmacology
(2
nd
ed
),New
York, Forgotten Books
Press
Maddison
. J. (
ed
) (2008).
Small Animal Clinical Pharmacology
, (2nd
ed
). Philadelphia, Saunders Elsevier Limited
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