Pharmacotherapy of Tuberculosis and Ectoparasite Infections in Poultry
PST 06107
Basic Veterinary Pharmacology
Session 30: Pharmacotherapy of Tuberculosis and
Ectoparasites
Infections in
Poultry
Learning Tasks
By
the end of this session students are expected to be able to:
Define Tuberculosis and
Ectoparasites
in Poultry
List signs and symptoms of Tuberculosis and
Ectoparasites
in Poultry
Describe pharmacological treatment of Tuberculosis and
Ectoparasites
in Poultry
Describe Control and Prevention of Tuberculosis and
Ectoparasites
in Poultry
Activity: Buzzing
is Tuberculosis in Poultry?
Definition of Tuberculosis in Poultry
Tuberculosis is a slowly spreading, chronic, granulomatous bacterial infection, characterized by gradual weight loss
Mycobacterium
avium
serovars
1 and 2 are the usual causes
Infected birds excrete the organism in their feces
Cadavers and offal may infect predators and cannibalistic
flockmates
Signs and Symptoms of Tuberculosis in Poultry
Signs
usually develop late in the infection when birds become thin and sluggish, and lameness may be seen
In chickens, granulomatous nodules of varying size are usually found in the liver, spleen, bone marrow, and intestine
Pharmacological Treatment of Tuberculosis in Poultry
Antituberculosis
drugs are not often used to treat chicken.
Ethambutol
Activity:
Brainstorming
What
are the prevention and control measures against Tuberculosis in Poultry??
Prevention and Control of Tuberculosis in Poultry
Depopulation
and good biosecurity practices including rodent control and screening
Addition of exotic birds to an exhibit should originate from a closed collection with no history of tuberculosis,
ie
, tuberculosis has not been reported previously or diagnosed on necropsy during the past 5 years
If no history is available, the birds should be quarantined or maintained in a separate exhibit away from the bird
aviary
Prevention and Control of Tuberculosis in Poultry
Cont.….
Therefore, it is recommended that endangered and valuable species be housed in individual exhibits to prevent transmission which is through ingestion of food or water contaminated with
M.
avium
ss
,
i.e
,
feces
from contagious birds
Infected poultry should be destroyed, and housing facilities thoroughly cleaned and disinfected using cresylic compounds
Key Points
Avian
tuberculosis is a chronic infectious disease characterized by the formation of granulomatous lesions in viscera, a progressive weight loss and death
The aetiological agent is Mycobacterium
avium
, a very resilient and acid-resistant
micro¬organism
Improved general sanitation has largely eliminated this infection
Evaluation
What
is Tuberculosis in Poultry?
What are the common signs and symptoms of Tuberculosis in Poultry?
What is the pharmacological treatment of Tuberculosis in Poultry?
What are the control measures against Tuberculosis in Poultry?
References
Riviere
J. E.,
Papich
M. G. (2009).
Veterinary Pharmacology and Therapeutics
(9
th
Ed) Iowa, Wiley-
Blackwel
Publishers
Hsu
W. H. (2008).
Handbook of Veterinary Pharmacology
(1
st
Ed) Iowa, Wiley-
Blackwel
Publishers
Kuafmann
J, (1996).
Parasitic infections of domestic animals
, (2
nd
ed
).Berlin,
Birkhäuser
Verlag
Press
Hoare
E. W. (2013).
A manual veterinary therapeutics & pharmacology
(2
nd
ed
),New
York, Forgotten Books
Press
Maddison
. J. (
ed
) (2008).
Small Animal Clinical Pharmacology
, (2nd
ed
). Philadelphia, Saunders Elsevier Limited
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