Description of Drugs affecting Blood
Session 27: Description of Drugs affecting Blood
Total Session Time: 60 minutes
Prerequisites
Learning Tasks
By the end of this session students are expected to be able to:
Resources Needed:
SESSION OVERVIEW
Activity/
Step Time Content
Method
1 05 minutes Presentation Introduction, Learning Objectives
Presentation/
2 10 minutes Indications of Drugs Affecting Blood
Buzzing
Presentation/
3 10 minutes Contraindications of Drugs Affecting Blood
Brainstorming
Description of Dose, Dosage and Course of
4 10 minutes Presentation
Drugs Affecting Blood
Presentation/ Side Effects and Adverse Effects of Drugs
5 10 minutes
Brainstorming Affecting Blood
Interactions and Precautions of Drugs
6 05 minutes Presentation
Affecting Blood
7 05 minutes Presentation Key Points
8 05 minutes Presentation Evaluation
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SESSION CONTENTS
STEP 1: Presentation of Session Title and Learning tasks (5 minutes)
READ or ASK students to read the learning objectives and clarify
ASK students if they have any questions before continuing.
STEP 2:Indications of drugs affecting blood (10 minutes)
Activity: Buzzing (5 minutes)
ASK students to pair up and buzz on the following question for 2 minutes
ALLOW few pairs to respond and let other pairs to add on points not mentioned
WRITE their response on the flip chart/board
CLARIFY and SUMMARIZE by using the content below
megaloblastic anaemia
STEP 3: Contraindications of Drugs Affecting Blood (10 Minutes)
Activity: Brainstorming (5 minutes)
Ask students to brainstorm on the following question:
ALLOW few students to respond
WRITE their responses on the flip chart/ board
CLARIFY and SUMMARISE by using the content below
PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide
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given with care to those people with peptic ulcers
alone for pernicious anaemia and other vitamin B12 deficiency states since it may
precipitate subacute combined degeneration of the spinal cord
be given before diagnosis fully established
including asthma and eczema, infection, active rheumatoid arthritis, severe hepatic
impairment and acute renal failure
STEP 4: Dose, Dosage and Course of Drugs Affecting Blood (10 minutes)
o Dose prophylactic, 1 tablet (200mg) daily; therapeutic, 1 tablet 2–3 times
daily until signs and symptoms disappear
in malabsorption state
o By mouth, vitamin B12 deficiency of dietary origin, 50–150 micrograms daily taken
between meals children 50–105 micrograms daily in 1–3 divided doses.
o By deep intramuscular injection into the gluteal muscle or by slow intravenous
bodyweight and iron deficit
o The product is not recommended to children under 14 years
PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide
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STEP 5: Side Effects and Adverse Effects of Drugs Affecting Blood
(10 Minute)
Activity: Brainstorming (5 minutes)
Ask students to brainstorm on the following question:
ALLOW few students to respond
WRITE their responses on the flip chart/ board
CLARIFY and SUMMARISE by using the content below
o Gastro-intestinal irritation can occur with iron salts example ferrous sulphate.
o Nausea and epigastric pain are dose-related and occur with high dose
o Oral iron, particularly modified-release preparations, can exacerbate diarrhea
o Nausea, headache, dizziness and fever
o Hypersensitivity reactions (including rash and pruritus) may occur.
o Injection-site reactions
o Hypokalaemia
o Thrombocytosis
o Chromaturia
o Nausea, vomiting and abdominal pain
o Flushing, dyspnoea and anaphylactic reactions
o Numbness, cramps and blurred Vision
o Pruritus, and rash;
STEP 6: Interactions and Precautions of Drugs Affecting Blood (5 minutes)
o Absorption of Ferrous sulphate is reduced by oral magnesium salts, calcium salts and
zinc
o Ferrous sulphate reduces absorption of ciprofloxacin and other fluoroquinolones,
levodopa, mycophenolates, Penicillamine, bisphosphonates and levothyroxines
drug
individual drug
PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide
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individual drug
STEP 7: Key points (5 minutes)
megaloblastic anemia.
than other preparations
deficiency states
STEP 8: Assessment (5 minutes)
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References
Pharmacotherapy: a pathophysiologic approach (9th ed.). New York,
McGraw-Hill Education.
Ministry Of Health and Social Welfare. 2013. Standard Treatment Guidelines &
National Essential Medicines List Tanzania Mainland (4th ed.). Dar es
salaam, Tanzania government printers.
Sally S.R, Jeanne C.S. 2000. Introductory Clinical Pharmacology (6th ed) New York,
Lippincott Williams and Wilkins.
School of Pharmaceutical sciences. 2011. Tanzania Pharmaceutical Handbook
(2nd ed.). Dar es Salaam, ARDHI University press.
The Royal Pharmaceutical Society of Great Britain. 2007. Martindale, the Extra
Pharmacopoeia (5TH ed). London, pharmaceutical press.
The Royal Pharmaceutical Society of Great Britain. 2009. British National Formulary
(59th ed). London, BMJ Group and RPS Publishing.
PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide
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