Description of Antispasmodic Drugs
Session 26: Description of Antispasmodic Drugs
Total Session Time: 60 minutes
Prerequisites
Learning Tasks
By the end of this session students are expected to be able to:
Resources Needed:
SESSION OVERVIEW
Activity/
Step Time Content
Method
1 05 minutes Presentation Introduction, Learning Tasks
Presentation
2 10 minutes Indications of antispasmodic drugs
Brainstorming
Presentation
3 05 minutes Contraindications of antispasmodic drugs
Buzzing
Dose, dosage and course of antispasmodic
4 10 minutes Presentation
drugs
Presentation Side effects and adverse effects of
5 10 minutes
Brainstorming antispasmodic drugs
Interactions and precautions of antispasmodic
6 10 minutes Presentation
drugs
7 05 minutes Presentation Key Points
8 05 minutes Presentation Evaluation
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SESSION CONTENTS
STEP 1: Presentation of Session Title and Learning tasks (5 minutes)
READ or ASK students to read the learning tasks and clarify
ASK students if they have any questions before continuing.
STEP 2: Indications of Antispasmodic Drugs (10 minutes)
Activity: Brainstorming (5 minutes)
ASK students to pair up and buzz on the following question for 2 minutes
ALLOW few pairs to respond and let other pairs to add on points not mentioned
WRITE their response on the flip chart/board
CLARIFY and SUMMARIZE by using the content below
o They include drugs such as Atropine sulfate, Dicycloverine hydrochloride,
Belladonna and Hyoscine butyl-bromide
The smooth muscle relaxant properties of anti-muscarinic and other antispasmodic drugs
may be useful in providing symptomatic relief gastro-intestinal disorders characterized by
smooth muscle spasms, especially in:
o Dysmenorrhea ( Hyoscine butyl-bromide)
o Irritable bowel syndrome
o Diverticular disease ( a condition associated with lower abdominal pain, anorexia,
fevers and disturbed bowel habit)
STEP 3: Contraindication of antispasmodic drugs (5 minutes)
Activity: Buzzing (5 minutes)
Ask students to brainstorm on the following question:
ALLOW few students to respond
WRITE their responses on the flip chart/ board
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CLARIFY and SUMMARISE by using the content below
STEP 4: Dose, Dosage and Course of Antispasmodic Drugs (10 minutes)
o 10–20mg 3 times daily; INFANT 6–24 months 5–10mg 3–4 times daily, 15 minutes
before feeds; CHILD 2–12 years 10mg 3 times daily
o 12.5mg every 8 hours
o By mouth: smooth muscle spasm, 20mg 4 times daily; CHILD 6– 12 years, 10mg 3
times daily. Irritable bowel syndrome, 10mg 3 times daily, increased if required up to
20mg 4 times daily
o By intramuscular or slow intravenous injection, acute spasm and spasm in diagnostic
procedures, 20mg repeated after 30 minutes if necessary (may be repeated more
frequently in endoscopy), max. 100mg daily
STEP 5: Side effects and adverse effects of antispasmodic drugs
(10 minutes)
Activity: Brainstorming (5 minutes)
Ask students to brainstorm on the following question:
ALLOW few students to respond?
WRITE their responses on the flip chart/ board
CLARIFY and SUMMARISE by using the content below
Side and adverse effects of Antispasmodics drugs:
o Constipation
o Transient bradycardia (followed by tachycardia, palpitation and arrhythmias)
o Reduced bronchial secretions
o Urinary urgency and retention
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o Dilatation of the pupils with loss of accommodation
o Photophobia
o Dry mouth
o Flushing
o Dryness of the skin
o Confusion (particularly in the elderly)
o Nausea
o Vomiting
o Giddiness
o Angle-closure glaucoma may occur.
STEP 6: Interaction and Precaution of Antispasmodic Drugs (10 minutes)
elderly
STEP 7: Key points (5 minutes)
characterized by smooth muscle spasms, especially in irritable bowel syndrome
dryness of the skin
STEP 7: Evaluation (5 minutes)
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References
Ministry of Health and Social Welfare. (2013). Standard Treatment Guidelines & National
Essential Medicines List Tanzania Mainland (4th ed.). Dar es salaam, Tanzania
government printers.
Pharmacotherapy: a pathophysiologic approach (9th ed.). New York, McGraw-Hill
Education.
Sally S.R & Jeanne C.S. 2000. Introductory Clinical Pharmacology (6th ed) New York,
Lippincott Williams and Wilkins
School of Pharmaceutical sciences. (2011).Tanzania Pharmaceutical Handbook (2nd ed.).
Dar es Salaam, ARDHI University press.
The Royal Pharmaceutical Society of Great Britain. (2007). Martindale, the Extra
Pharmacopoeia (5TH ed). London, pharmaceutical press.
The Royal Pharmaceutical Society of Great Britain. (2009). British Nationanal Formulary
(59th ed). London, BMJ Group and RPS Publishing.
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