Description of Anti Hemorrhoid Drugs – PST04211 Basic Pharmacology

NTA Level 4 • Semester 2 • PST04211

Description of Anti Hemorrhoid Drugs

Basic Pharmacology • Source Session/Topic 25
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 25: Description of Anti Hemorrhoid Drugs

Total Session Time: 60 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• List indications of anti hemorrhoid drugs
• List contraindication of anti hemorrhoid drugs
• Describe dose, dosage and course of anti hemorrhoid drugs
• List side effects and adverse effects of anti hemorrhoid drugs
• Describe interactions and precautions of anti hemorrhoid drugs

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers
• Overhead projector and computer

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Tasks

Presentation/

2 10 minutes Indications of Anti hemorrhoid Drugs

Buzzing

3 05 minutes Presentation Contraindications of Anti hemorrhoid Drugs

Dose, Dosage and Course of Anti hemorrhoid

4 10 minutes Presentation

Drugs

Presentation/ Side effects and Adverse Effects of Anti

5 15 minutes

Brainstorming hemorrhoids Drugs

Interactions and Precautions of Anti

6 05 minutes Presentation

hemorrhoid Drugs

7 05 minutes Presentation Key Points

8 05 minutes Presentation Evaluation

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SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing.

STEP 2: Indications of Anti hemorrhoid Drugs (10 minutes)

Activity: Buzzing (5 minutes)

ASK students to pair up and buzz on the following question for 2 minutes

• What are the indications of anti hemorrhoid drugs?

ALLOW few pairs to respond and let other pairs to add on points not mentioned

WRITE their response on the flip chart/board

CLARIFY and SUMMARIZE by using the content below

• Anusol suppository/or ointment which contains: Benzyl benzoate 33 mg, bismuth oxide
24 mg, bismuth subgallate 59 mg, hydrocortisone acetate 10 mg, Peru balsam 49 mg and
zinc oxide 296 mg is used in management of hemorrhoids in adults

o Ingredients contained in anusol suppository such as bismuth subgallate, zinc oxide are

mild astringents which give symptomatic relief in hemorrhoids

• Bismuth subgallate: With 1% hydrocortisone ointment is used in management of

hemorrhoids. Hydrocortisone helps to relieve rectal pain, itching, bloody diarrhoea, and

bleeding by reducing swelling (inflammation) directly in the rectum and anus

• Paracetamol is used to relieve pain and inflammation in hemorrhoids
• Proctosedyl suppository or ointment is used as a second choice in hemorrhoids
• Many proprietary preparations also contain lubricants, mild antiseptics or vasoconstrictors

that reduce swelling and relieve itching and discomfort by tightening blood vessels

• Phenylephrine is an example of a vasoconstrictor (contained in Preparation) used in

hemorrhoids

STEP 3: Contraindications of Anti hemorrhoids Drugs (5 minutes)

• Anti hemorrhoid drugs containing local anaesthetics should be avoided in infants and

children

• Allergic reactions/hypersensitivity to any of the ingredients of anti hemorrhoid

preparation

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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STEP 4: Dose, Dosage and Course of Anti hemorrhoid Drugs (10 minutes)

• One Anusol suppository is inserted night only OR and morning after bowel movement for

a maximum of seven days

• A second choice Proctosedyl suppository or ointment is used once or twice a day, that is

12 hourly

• Bismuth subgallate with 1% hydrocortisone ointment is used once or twice a day, that is

24 hourly or 12 hourly

STEP 5: Side Effects and Adverse Effects of Anti hemorrhoids Drugs

(15 minutes)

Activity: Brainstorming (5 minutes)

Ask students to brainstorm on the following question:

• What are side effects and adverse effects of anti hemorrhoid drugs?

ALLOW few students to respond

WRITE their responses on the flip chart/ board

CLARIFY and SUMMARISE by using the content below

• Side effects of anti hemorrhoid drugs are rare: Burning, itching, dryness, skin/hair follicle

irritation, and changes in skin colour around the rectal area may occur

• Rarely, it is possible corticosteroids and other ingredients of anusol will be absorbed into

the bloodstream leading to toxicity. Refer Lecture on corticosteroids for side effects

STEP 6: Interactions and Precautions Anti hemorrhoids Drugs (5 minutes)

• Anusol suppository and most anti hemorrhoid drugs are not recommended in children
• Precaution should be taken when using anti hemorrhoid preparations containing

vasoconstrictors such phenylephrine if a patients has hypertension, heart problems,

thyroid problems or diabetes

• Interactions of anti hemorrhoid drugs are rare, may occur when corticosteroids and other

ingredients are absorbed into blood stream

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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STEP 7: Key Points (5 minutes)

• Only few drugs are available for management of hemorrhoids
• Early stages of the disease could be effectively managed lifestyle changes, fiber

supplement, use of food softeners, and drugs mainly topical ointments and suppositories

• The more advanced hemorrhoid stages need some type of surgery
• Astringents (drying agents) help shrink hemorrhoids by pulling water out of the swollen

tissue. This, in turn, helps relieve itching, burning, and irritation

STEP 8: Evaluation (5 minutes)

• What drugs are indicated for Hemorrhoids?
• What are contraindications of anti hemorrhoids?
• What are the dose, dosage and course of anti hemorrhoid drugs?
• What are side effects of anti hemorrhoids?

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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References

Ministry Of Health and Social Welfare. (2013). Standard Treatment Guidelines &

National Essential Medicines List Tanzania Mainland (4th ed.). Dar- es-

salaam, Tanzania government printers.

The Royal Pharmaceutical Society of Great Britain. (2009). British National Formulary

(59th ed). London, BMJ Group and RPS Publishing.

Sally, S.R., & Jeanne, C.S. (2000). Introductory Clinical Pharmacology (6th ed).

New York, Lippincott Williams and Wilkins.

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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