Description of Cathartic Drugs – PST04211 Basic Pharmacology

NTA Level 4 • Semester 2 • PST04211

Description of Cathartic Drugs

Basic Pharmacology • Source Session/Topic 24
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 24: Description of Cathartic Drugs

Total Session Time: 60 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• List indications of cathartics drugs
• List contraindications of cathartics drugs
• Describe dose, dosage and course of cathartics drugs
• List side effects and adverse effects of cathartics drugs
• Describe interaction and precaution of cathartics drugs

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers
• Overhead projector and computer

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Tasks

Presentation/

2 10 minutes Indications of Cathartic Drugs

Buzzing

Presentation/

3 10 minutes Contraindications of Cathartic Drugs

Brainstorming

4 10 minutes Presentation Dose, Dosage and Course of Cathartic Drugs

Presentation/ Side Effects and Adverse Effects of

5 10 minutes

Brainstorming Cathartics Drugs

Interactions and Precautions of Cathartic

6 05minutes Presentation

Drugs

7 05 minutes Presentation Key Points

8 05 minutes Presentation Evaluation

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SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing.

STEP 2: Indications of Cathartic Drugs (10 minutes)

Activity: Buzzing (5 minutes)

ASK students to pair up and buzz on the following question for 2 minutes

• Mention cathartic drugs.
• What are indications of cathartic drugs?

ALLOW few pairs to respond and let other pairs to add on points not mentioned

WRITE their response on the flip chart/board

CLARIFY and SUMMARIZE by using the content below

• Also called stimulus laxatives and include lactulose and bisacodyl
• Cathartic drugs are indicated in :

o Constipation

o Preparation for radiological procedure

o Preparation for surgery

o Lactulose is indicated in hepatic encephalopathy (portal systemic encephalopathy)

• Commonly cathartics are bisacodyl and lactulose

STEP 3: Contraindications of Cathartic Drugs (10 minutes)

Activity: Brainstorming (5 minutes)

Ask students to brainstorm on the following question:

• What are contraindications of cathartic drugs?

ALLOW few students to respond

WRITE their responses on the flip chart/ board

CLARIFY and SUMMARISE by using the content below

• Lactulose are contraindicated in patients with :

o Intestinal obstruction

o Galactosaemia

• Bisacodyl are contraindicated in:

o Acute surgical condition

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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o Acute inflammatory bowel diseases

o Severe dehydration

STEP 4: Dose, Dosage and Course of Cathartic Drugs (10 minutes)

• Bisacodyl

o For treatment of constipation:

 5-10mg orally at night

 Or suppositories 10mg in the morning

o Preparation for surgery and radiological procedures:

 10-20 mg orally the night before procedure

 Suppositories 10mg 1-2 hours before procedure

• Lactulose

o For treatment of constipation

 15ml twice daily adjust according to response

o Hepatic encephalopathy

 30-50ml three times daily

STEP 5: Side Effects and Adverse Effects of Cathartic Drugs (10 Minutes)

Activity: Brainstorming (5 minutes)

Ask students to brainstorm on the following question:

• What are side effects and adverse effects of cathartic drugs?

ALLOW few students to respond

WRITE their responses on the flip chart/ board

CLARIFY and SUMMARISE by using the content below

• The side effects and adverse effects of Lactulose are:

o Nausea

o Vomiting

o Flatulence

o Cramps

o Abdominal discomfort

• The side effects and adverse effects of bisacodyl are:

o Nausea

o Vomiting

o Colitis

o Local irritation on suppository application

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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STEP 6: Interactions and Precautions of Cathartic Drugs (5 minutes)

• Interactions

o Lactulose enhances the anticoagulant effect of coumarins

• Precautions

o Avoid lactulose in lactose intolence

o Avoid excessive use in hypokalaemia

Step 7: Key Points (5minutes)

• Cathartic drugs are indicated to patients with constipation and in preparation for surgical

and radiological procedures

• Cathartic drugs are contraindicated in patients with intestinal obstruction and severe

dehydration

• Cathartic drugs can be given orally or as suppositories
• Nausea and vomiting are common side effects of Cathartic drugs
• Caution should be taken to patient with lactose intolerance

STEP 8: Evaluation (5minutes)

• What are the indications of Cathartic drugs?
• What are the Contraindication of Cathartic drugs?
• What are side effects and adverse effects of Cathartic drugs?

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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References

Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael

(2014). Pharmacotherapy: a pathophysiologic approach (9th ed.). New

York, McGraw-Hill Education.

Ministry Of Health and Social Welfare. 2013. Standard Treatment Guidelines &

National Essential Medicines List Tanzania Mainland (4th ed.). Dar es

salaam, Tanzania government printers.

Sally S.R, Jeanne C.S. 2000. Introductory Clinical Pharmacology (6th ed) New

York, Lippincott Williams and Wilkins

School of Pharmaceutical sciences. 2011. Tanzania Pharmaceutical Handbook

(2nd ed.). Dar es Salaam, ARDHI University press.

The Royal Pharmaceutical Society of Great Britain. 2007. Martindale, the Extra

Pharmacopoeia (5TH ed). London, pharmaceutical press.

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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