Identification of Formula Needed in Pharmaceutical Compounding from the References – PST04209 Compounding of Pharmaceutical Preparations

NTA Level 4 • Semester 2 • PST04209

Identification of Formula Needed in Pharmaceutical Compounding from the References

Compounding of Pharmaceutical Preparations • Source Session/Topic 6
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 6: Identification of Formula Needed in

Pharmaceutical Compounding from the References

Total Session Time: 120 minutes + 4 hours of Practical

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• List References /Compendia Used in Compounding of Pharmaceutical Preparations
• Identify Formula for Pharmaceutical Preparation

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board ,chalk and whiteboard markers
• LCD projector and computer

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Tasks

35 minutes Presentation References /Compendia Used in Compounding

2 of Pharmaceutical Preparations

Buzzing

60 minutes Presentation Identification of Formula for Pharmaceutical

3 Preparation

Demonstration

4 10 minutes Presentation Key Points

5 10 minutes Presentation Evaluation

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 30

SESSION CONTENTS

STEP1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing

STEP 2: References/ Compendia Used in Compounding of Pharmaceutical

Preparations (35 Minutes)

• A reference book is a book containing useful facts or specially organized information, as

an encyclopedia, dictionary, or atlas. Or is a book intended to be consulted for

information on specific matters rather than to read from beginning to the end.

o These books have been written as a student guide to extemporaneous pharmaceutical

compounding and dispensing. It has been designed to assist the student compounder

in understanding the key dosage forms encountered within extemporaneous

dispensing.

Activity: Buzzing (5 minutes)

ASK students to pair up and buzz on the following question for 2 minutes

• What are the references/ Compendia used in compounding?

ALLOW few pairs to respond and let other pairs to add on points not mentioned

WRITE their response on the flip chart/board

CLARIFY and SUMMARIZE by using the content below

• The following are the reference books used in compounding:

o Tanzania Pharmaceutical Handbook (TPH)

o Pharmaceutical Codex (PCx)

o British Pharmacopoeia (BP)

o United State Pharmacopoeia (USP)

o Martindale‟s Extra Pharmacopoeia

o Remington: The Science and Practice of Pharmacy 21st Edition

o The Tanganyika Formulary

STEP 3: Identification of Formula for Pharmaceutical Preparation (60

Minutes)

• After comprehended the request in the prescription, a compounder has to identify the

correct formula from the reference book

• The correct formulas from the reference book can be obtain through the following ways:
CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 31

o Find the name of the pharmaceutical preparation to be compounded through table

of contents of the reference book and go to formulation, e.g. solution.

o The formulation in the content indicates the page where the respective formula is

indicated.

o Find the name of the pharmaceutical preparation to be compounded through the

index of the reference book

o The index indicates the number of page where the respective formula is indicated

Below are official formulas obtained from the reference book (TPH) under the indicated

table of content of the book

• AQUEOUS IODINE SOLUTION PCx (Syn. Lugol‟s Solution)
Iodine………………………………………………………….. 5.0 g
Potassium iodide………………………………………………. 10.0 g

Purified water freshly boiled and cooled ……………………… to 100mL

• WEAK IODINE SOLUTION PCx. (Syn. Iodine Tincture)
Iodine………………………………………………………. 2.5 g
Potassium iodide…………………………………………… 2.5 g
Purified water, freshly boiled and cooled………………….. 2.5 g
Alcohol (90%)……………………………………………… to 100.0 mL

Activity: Demonstration (50 minutes)

DIVIDE students in small manageable groups.

PREPARE formula from a reference book for demonstration

POSITION students so that everyone can see and hear

REVIEW steps of that skill with students using a reference book

REFER students to the Tanzania Pharmaceutical Handbook (TPH)

DEMONSTRATE the procedure of identifying a formula from a reference book

ALLOW one student from each group to do a return demonstration and let others comment

on it

CLARIFY and SUMMARIZE the procedures to identify a Formula for Pharmaceutical

Preparation

INFORM the students that “every student will practice in the laboratory under supervision

until is competent”

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 32

STEP 4: Key Points (10 minutes)

• A reference book is a book containing useful facts or specially organized information, as

an encyclopedia, dictionary.

• After comprehended the request in the prescription, a compounder has to identify the

correct formula from the reference book

• The correct formulas from the reference book can be obtain through table of content and

index of the respective book.

STEP 5: Evaluation (10 minutes)

• What is a reference book?
• How the correct formula from the reference book can be identified?

STEP 6: Practice (4)

• INFORM the students that they have to practice in the laboratory in identification of

formula needed in pharmaceutical compounding from the references book

o BENZOIC ACID SOLUTION (TPH)

o SALICYLIC ACID OINTMENT (TPH).

o SALICYLIC ACID AND SULPHUR OINTMENT (TPH)

o CHLOROFORM WATER, DOUBLE STRENGTH (TPH)

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 33

References

Pharmaceutical Society of Great Britain., & . Department of Pharmaceutical Sciences. (1994).

The Pharmaceutical Codex, Principles and Practice of Pharmaceutics (W. Lund Ed. 12th

ed.). London,: Pharmaceutical .

Senya, S. S., Mwasha, C. Y. S., Muyinga, A. M., Amiri, R. I., & Mauga, E. A. S. K. (2011).

Tanzania Pharmaceutical Handbook (2nd ed.). Dar es salaam: School of Pharmaceutical

Sciences, Institute of Allied Health Sciences, Muhimbili University of Health and Allied

Health Sciences.

United States Pharmacopeial Convention. Committee of Revision. (2013). The United States

pharmacopeia (pp. v.). Rockville, Md.: United States Pharmacopeial Convention, Inc.

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 34

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