Calculations of Dilution Using Alligation
Session 8: Calculations of Dilution Using Alligation
Alternate and Medial
Total Session Time: 120 minutes + 1 hour Assignment
Prerequisites
Students Learning Tasks
By the end of this session students are expected to be able to:
Resources Needed:
SESSION OVERVIEW
|Step |Time |Activity/ |Content |
| | |Method | |
|1 |05 minutes |Presentation |Introduction, Learning Tasks |
|2 |40 minutes |Presentation |Dilution by Using Alligation |
| | |Group |Alternate |
| | |discussion | |
|3 |40 minutes |Presentation |Dilution by Using Alligation Medial |
| | |Group | |
| | |discussion | |
|4 |05 minutes |Presentation |Key Points |
|5 |15 minutes |Presentation |Evaluation |
|6 |15 minutes |Presentation | Assignment |
SESSION CONTENTS
STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)
READ or ASK students to read the learning tasks and clarify
ASK students if they have any questions before continuing.
STEP 2: Dilution by Using Alligation Alternate (40 Minutes)
o Alligation is an arithmetic method of solving problems that involve
the mixing of solutions or mixtures of solids possessing different
percentage strengths
o This is a method by which we can calculate the number of parts of two
or more components of a given strength when they have to be mixed to
prepare a mixture of desired strength
Example:
In what proportion should alcohol of 95% and 50% strengths be mixed to
make 70% alcohol?
Solution for the above question
| 95 |
| 50 |
Totals 1000ml 284ml
STEP 4: Key Points (5 minutes)
or mixtures of solids possessing different percent strengths
or more components of a known strength that when mixed provide a mixture
of desired strength
solution, given the % strength of the individual components using the
alligation alternate
strength of a mixture of two or more substances of known quality and
concentration may be easily calculated
STEP 5: Evaluation (15 minutes)
respectively, 50%, 20% and 5% of zinc ointment. In what proportion should
they be mixed to prepare a 10% zinc oxide?
STEP 6: Take Home Assignment (15 minutes)
|Activity: Take home Assignment (15 minutes) |
| |
|ASK each individual student to do the following assignment |
| |
| |
|In what proportion should 20% benzocaine ointment be mixed with an |
|ointment base to produce a 2.5% benzocaine ointment? |
| |
|ALLOCATE time for students to do the assignment and submit |
| |
|REFER students to recommended references |
References
Ansel, H. C & Stocklosa, M. J. (2001). Pharmaceutical Calculations (11th
ed.). Philadelphia, United States: LIPPINCOTT WILLIAMS & WILKINS
Ansel, H. C (2010) Pharmaceutical Calculations (13rd ed.). Philadelphia,
United States: LIPPINCOTT WILLIAMS & WILKINS
Senya, S. S, Mwasha, C.Y, Muyinga, A. M, Amiri,R. I. and Mauga E.A.S.K.
(2011) Tanzania Pharmaceutical Handbook (2nd ed.). Dar eS Salaam,
Tanzania: School of Pharmaceutical Sciences.
New Jersey: John Wiley & Sons, Inc
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