Pharmacotherapy of Aspiration Pneumonia and Pneumonia in Cattle and Goat – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Aspiration Pneumonia and Pneumonia in Cattle and Goat

Basic Veterinary Pharmacology • Source Session/Topic 15
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PST 06107

Basic Veterinary Pharmacology

Session 15:

Pharmacotherapy of Aspiration Pneumonia and Pneumonia in Cattle and Goat

Learning Tasks

By

the end of this session students are expected to be able to:

Define Aspiration Pneumonia and Pneumonia in Cattle and Goat

List signs and symptoms of Aspiration Pneumonia and Pneumonia in Cattle and Goat

Explain the pharmacological treatment of Aspiration Pneumonia and Pneumonia in Cattle and Goat

Explain the control and prevention of Aspiration Pneumonia and Pneumonia in Cattle and Goat

Activity: Buzzing

What

is Pneumonia in

Cattle

?

Definition of Pneumonia in Cattle and Goat

Pneumomnia

is an inflammation of the pulmonary parenchyma usually accompanied by inflammation of the bronchioles and often by pleurisy

Important pathogens that cause pneumonia in cattle are;

Mannheimia

haemolytica

serotype A

,

Haemophilus

somnus

,

P.

multocida

,

Mycobacterium

bovis

,

Mycoplasma

mycoides

subspecies

mycoides

small colony type,

Parainfluenza

virus 3,

Bovine respiratory syncytial virus,

Bovine

herpes virus 1

Signs and Symptoms of Aspiration Pneumonia in Cattle and Goat

It

is manifested clinically by an increase in respiratory rate, cough, abnormal breath sounds on auscultation and, in most bacterial pneumonias, by evidence of toxemia.

Bronchopnemonia

is usually accompanied by a moist, painful cough; interstitial pneumonia is characterized by frequent, hacking coughs, often in paroxysms.

The presence of nasal discharge depends on accompanying inflammation of the upper respiratory tract.

Pharmacological

treatment of Pneumonia in Cattle and Goat

Sulfamethazine

:

initial

220 mg/kg;

maintenance

110 mg/kg q 24 h, PO for 5-7 days, or
Procaine penicillin G, 22,000 IU/kg, aqueous suspension, IM or SC q 24 h for 3 to 5 days, or

Ampicillin

trihydrate

22 mg/kg, IM, SC, q 24 h for 3-6 days, or

Amoxicillin

trihydrate

11 mg/kg, IM, SC, q 24 h for 3-7 days, or

Oxytetracycline

hydrochloride 11 mg/kg, SC, q 24 h or long acting formulation, 20 mg/kg, IM, q 48 h for 3-5 days, or

Tylosin

44 mg/kg, IM, q 24 h for 3-5 days.

Activity:

Brainstorming

What are the prevention measures for Pneumonia in Cattle?

Prevention

and Control of Pneumonia in Cattle and Goat

Given

the multi-factorial nature of the disease, good calf pneumonia control programmes rely on implementing an appropriate vaccine strategy, alongside improvements to management practices to reduce the risk of disease

Provide appropriate calf housing with good ventilation; plenty of air, no draughts and

a well

bedded dry lying area

Prevent scour and manage outbreak properly if they occur

Prevention

and Control of Pneumonia in Cattle and Goat

Cont

Prevent BVD in the herd through culling and testing practices

Outdoor reared calves are generally at lower risk of pneumonia

Implement vaccination program.

Vaccines are available that will enhance protection against the common viral and some of the bacterial causes of pneumonia

Calves can be vaccinated from two weeks of age (i.e. IBR vaccine).

The vaccination program is two shots, four weeks apart

A booster dose should be given before the next risk period

Key Points

Several

species of bacteria have been isolated in Cattle, but the most commonly found species are

Mannheimia

haemolytica

. (Formerly known as

Pasteurella

haemolytica

),

P.

multocida

,

Histophilus

(Haemophilus)

somnus

and

Mycoplasma

spp.

M.

haemolytica

.

(P.

haemolytica

)

and

P.

multocida

are the most important bacteria involved in Cattle Pneumonia

.

Early recognition by trained personnel skilled at detecting the early clinical signs of disease followed by treatment with antibiotics is essential for successful therapy

Evaluation

What

is aspiration pneumonia?

What are the common signs and symptoms of pneumonia in cattle?

What is the pharmacological treatment of pneumonia in Cattle?

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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