Description of Antiemetic Drugs
Session 21: Description of Antiemetic Drugs
Total Session Time: 120 minutes
Prerequisites
Learning Tasks
By the end of this session students are expected to be able to:
Resources Needed:
SESSION OVERVIEW
Activity/
Step Time Content
Method
1 05 minutes Presentation Introduction, Learning Tasks
Presentation/
2 20 minutes Indications of Antiemetic Drugs
Buzzing
Presentation/
3 20 minutes Contraindications of Antiemetic Drugs
Brainstorming
Dose, Dosage and Course of Antiemetic
4 30 minutes Presentation
Drugs
Presentation/ Side Effects and Adverse Effects of
5 20 minutes
Brainstorming Antiemetic Drugs
Interactions and Precautions Antiemetic
6 15 minutes Presentation
Drugs
7 05 minutes Presentation Key Points
8 05 minutes Presentation Evaluation
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STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)
READ or ASK students to read the learning tasks and clarify
ASK students if they have any questions before continuing.
STEP 2: Listing Indications of Antiemetic Drugs (20minutes)
Activity: Buzzing (5 minutes)
ASK students to pair up and buzz on the following question for 2 minutes
ALLOW few pairs to respond and let other pairs to add on points not mentioned
WRITE their response on the flip chart/board
CLARIFY and SUMMARIZE by using the content below
o Chlorpromazine
o Metoclopramide
o Promethazine hydrochloride
o Droperidone
o Donperidone
o Adverse effects from medications
o Systemic disorders: pregnancy, vestibular dysfunction, increased pressure,
hepatobiliary disorders, radiation or chemotherapy, and gastrointestinal obstruction,
dysmotility
o Infections: central nervous system infection, peritonitis
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STEP 3: Contraindications of Antiemetic Drugs (20 minutes)
Activity: Brainstorming (5 minutes)
Ask students to brainstorm on the following question:
What are contraindications of antiemetic drugs?
ALLOW few students to respond
WRITE their responses on the flip chart/ board
CLARIFY and SUMMARISE by using the content below
drugs
o Narrow angle glaucoma
o Severe liver disease
o Cardiovascular disease
STEP 4: Dose, Dosage and Course of Antiemetic Drugs (30 minutes)
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STEP 5: Side Effects and Adverse Effects of Antiemetic Drugs (20
minutes)
Activity: Brainstorming (5 minutes)
Ask students to brainstorm on the following question:
What are side effects and adverse effects of antiemetic drugs?
ALLOW few students to respond
WRITE their responses on the flip chart/ board
CLARIFY and SUMMARISE by using the content below
o Headache
o Dizziness
o Constipation
o Drowsiness
o Sedation
o Dry mouth
o Hypertension
o Hypotension
o Nasal congestion
o Diarrhea
STEP 6: Interactions and Precautions of Antiemetic Drugs (15minutes)
o Severe nausea and vomiting
o Obstructive diseases of gastro intestinal or genitourinary system
o Hypertension
o Sleep apnea
o Epilepsy
o Central nervous system depressants such as:
Sedatives
Antidepressants
Opiates
Hypnotics
Antianxiety drugs
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o Also exaggerate the anticholinergic effects of antihistamine, antidepressants,
phenothiazines and disopyramide
o Antiacids decrease absorption of antiemetic
Step 7: Key Points (5 minutes)
systemic disorders and effects of other medications
liver and cardiovascular diseases
sedation
gastrointestinal obstructive condition
effects of anticholinergic drugs
STEP 8: Evaluation (5 minutes)
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References
Ministry Of Health and Social Welfare. (2013). Standard Treatment Guidelines & National
Essential Medicines List Tanzania Mainland (4th ed.). Dar es salaam, Tanzania
government printers.
Pharmacotherapy: A Pathophysiologic Approach (9th ed.). New York, McGraw-Hill
Education.
Sally, S.R, Jeanne C.S. (2000). Introductory Clinical Pharmacology (6th ed) New York,
Lippincott Williams and Wilkins
School of Pharmaceutical sciences. (2011).Tanzania Pharmaceutical Handbook (2nd ed.). Dar
es Salaam, ARDHI University press.
The Royal Pharmaceutical Society of Great Britain. (2007). Martindale, The Extra
Pharmacopoeia (5TH ed). London, pharmaceutical press.
The Royal Pharmaceutical Society of Great Britain. (2009). British National Formulary
(59th ed). London, BMJ Group and RPS Publishing.
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