Common Disorders of Connective Tissues – PST04103 Human Anatomy and Physiology

NTA Level 4 • Semester 1 • PST04103

Common Disorders of Connective Tissues

Human Anatomy and Physiology • Source Session/Topic 7
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 7: Common Disorders of Connective Tissues

Total Session Time: 60 minutes

Prerequisites

• Session 5 & 6: Structure and function of connective tissue and bone

tissue

Learning Tasks

By the end of this session, students are expected to be able to:

• Define Connective Tissue Diseases
• Mention Common Types of Connective Tissue Diseases
• Explain Common Connective Tissue Diseases

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board, chalk and whiteboard markers
• Overhead projector
• Computer

SESSION OVERVIEW

|Step |Time |Activity/ |Content |

| | |Method | |

|1 |05 minutes |Presentation |Introduction, Learning Tasks |

|2 |05 minutes |Presentation |Definition of Connective Tissue |

| | |Buzzing |Diseases |

|3 | |Presentation |Common types of Connective Tissue |

| |05 minutes |Brainstorming |Diseases |

|4 | |Presentation |Common Connective Tissue Diseases |

| |35 minutes |Small Group | |

| | |Discussion | |

|5 |05 minutes |Presentation |Key Points |

|6 |05 minutes |Presentation |Evaluation |

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing

STEP 2: Definition of Connective Tissue Diseases (5 minutes)

|Activity: buzzing(5 minutes) |

| |

|Ask students to buzz on the following question: |

| |

|What are connective tissue diseases? |

| |

|ALLOW students to buzz |

| |

|WRITE their responses on the flip chart/ board |

| |

|CLARIFY and SUMMARISE by using the content below |

• A connective tissue diseases are diseases that affect the joints (parts

of the body that connect the structures of the body together).

o It is presented by the inflammation of the joints (arthritis)

o It may be infective or non-infective.

o In most cases, all signs of inflammation are present (swollen joints,

hot, tender and red) and there is limitation of movements.

STEP 3: Common Types of Connective Tissue Diseases ( 5 minutes)

• Acute pyrogenic arthritis
• Gout
• Chronic joint disease
• Osteoarthritis
• Generalized bone disease

o Osteomalacia

o Osteoporosis

STEP 4: Common Connective Tissue Diseases (35 minutes)

|Activity: Small Group Discussion ( 15 minutes) |

| |

|DIVIDE students into small manageable groups |

| |

|ASK students to discuss on the following question |

|What are the common of connective tissue diseases? |

| |

|ALLOW students to discuss for 15 minutes |

| |

|ALLOW few groups to present and the rest to add points not mentioned |

| |

|CLARIFY and SUMMARIZE by using the contents below |

• Acute pyrogenic arthritis

o This is the infection of the joints by pus-producing bacteria

o It is caused by any pyrogenic bacteria like staphylococci.

o The infection may start suddenly without any obvious cause or may occur

from other septic focus nearby like osteomyelitis

o The patients complain of pain, swelling and reduced movement of the joint

• Gout

o This is arthritis due to congenital abnormality of uric acid metabolism,

leading to abnormal high uric acid in the blood.

o Uric acid is deposited in joints and also around the joints and in the

ear cartilages.

o The kidney may be damaged and kidney stones may form in them.

o The disease is commonest in men over 40 years.

o The acute episodes may be precipitated by alcohol excess, surgery,

infections or treatment with thiazide diuretics which raise serum uric

acid even in normal people.

o Patients experience irritability and malaise a day or two before acute

attack of gout and sudden severe pain starts in one joint especially that

of big toe.

• Chronic joint disease

o Rheumatoid arthritis

▪ The cause is thought to be abnormal immunological reactions.
▪ Women are affected then men at the age between 20 – 40 years and

psychological factors are often involved.

▪ The patient notices pain and stiffness of a joint, then swollen

joints and finally radiate to the wrist, knee and hips.

o Osteoarthritis

▪ This is due to a degeneration of the articular cartilage of joints.
▪ It is common to older people.
▪ The exact cause is not certain but it comes with age particularly in

people who have done heavy work.

▪ It also occurs after injuries that have involved a joint or bone.
▪ The only symptom is aching pain in the joints, worse at the end of

the day and relieved by rest.

• Generalized bone disease

o Osteoporosis

▪ It is a condition in which the bones are thinned though their

composition is normal.

▪ It can be caused by immobilization; when a limb is put in plaster or

stay in bed for a long time, menopause in women, old age, Cushing’s

syndrome and steroid treatment.

▪ The pain occurs only when there is bone fracture.

o Osteomalacia

▪ This is a different form of weakening of bones due to vitamin D

deficiency.

▪ It is common in adults.
▪ There are bone pains, often muscular weakness and may be tetany.
▪ The weakened bones may collapse and deform.

STEP 4: Key Points (5 minutes)

• A connective tissue disease is any disease that affects the joints and

is presented by the inflammation of the joints.

• Connective tissue diseases include acute pyrogenic arthritis, gout,

rheumatoid arthritis, osteoarthritis, osteoporosis and osteomalacia.

STEP 5: Evaluation (5minutes)

• What are connective tissue diseases?
• What are the common connective tissue diseases?

References

Nicholson, N.W. (1988). Non communicable diseases in adults. Nairobi,

Kenya: African

Medical and Research Foundation

Scalon, V.C., & Sanders, T. (2007). Essentials of anatomy and physiology

(5th ed.).

Philadelphia,NY: F.A Davis

Tortora, J.G., & Derrickson, B. (2009). Principles of anatomy and

physiology (12th

ed.).Danvers, MA:John Wiley & Sons

Waugh,A.,& Wilson, J.W.K. (2001): Anatomy and Physiology in Health and

Illness(9th

ed.). Totternham, London: Churchill Livingstone

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