Pharmacotherapy of Aspergillosis, Campylobacteriosis and Amoebiasis in Dogs – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Aspergillosis, Campylobacteriosis and Amoebiasis in Dogs

Basic Veterinary Pharmacology • Source Session/Topic 34
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PST 06107

Basic Veterinary Pharmacology

Session 34: Pharmacotherapy of Aspergillosis, Campylobacteriosis,

and Amoebiasis

in Dogs

Learning Tasks

By

the end of this session students are expected to be able to:

Define

aspergillosis

,

campylobacteriosis

and

amebiasis

in dogs

List signs and symptoms of

aspergillosis

,

campylobacteriosis

and

amebiasis

in dogs

Describe pharmacological treatment of

aspergillosis

,

campylobacteriosis

and

amebiasis

in dogs

Describe control and prevention of

aspergillosis

,

campylobacteriosis

andamebiasis

in dogs

Activity: Buzzing

What is Aspergillosis in Dog?

Definition of Aspergillosis

in

Dogs

Aspergillosis is caused by a number of

Aspergillus

spp

,

especially

A

.

fumigatus

.

It is primarily a respiratory infection that may become generalized.

Nasal and

paranasal

tissues of dogs are most commonly infected

Sign And Symptoms Of Aspergillosis In Dogs

Lethargy

Nasal pain

Ulceration of the nares, sneezing, unilateral or bilateral sanguinopurulent nasal discharge, frontal sinus osteomyelitis, and epistaxis

Lesions may involve the eyes

A layer of gray-black necrotic material and fungal growth may cover the mucosa of the nasal and paranasal sinuses

Pharmacological Treatment of Aspergillosis in Dog

Griseofulvin

15-20 mg/kg, PO with fatty food, q 24 h for 7-14 days, or
Ketoconazole 15 mg/kg, PO, q 12 h for dogs and 10 mg/kg, PO, q 12 h to cats for 6-8

wk

Activity:

Brainstorming

What

are the prevention and control measures for Aspergillosis in Dog?

Prevention and Control of Aspergillosis in Dog

General

good health will help ensure a strong healthy immune system to ward off this opportunistic disease

Keeping dogs indoors may be helpful, as it will limit access to grass clippings, hay, straw, and other substances where the

Aspergillus

fungus can be found

Dogs with the nasal version should be monitored for reduced nasal discharge, while those with disseminated disease need to be monitored with urine analysis and via X-ray every one to two months

Key Points

Aspergillosis

is an infection, growth, or allergic response caused by the Aspergillus fungus

This fungus grows on dead leaves, stored grain, compost piles, or other decaying vegetation

Treatment varies depending on whether the disease is nasal or disseminated

Evaluation

What

is Aspergillosis in Dog?

What are the common signs and symptoms of Aspergillosis in Dog?

What is the pharmacological treatment of Aspergillosis in Dog?

What are the control measures against Aspergillosis in Dog?

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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