Pharmacotherapy of Mycoplasma Synoviae Infection and Staphylococcosis in Poultry
PST 06107
Basic Veterinary Pharmacology
Session 26: Pharmacotherapy of Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
Learning Tasks
By
the end of this session students are expected to be able to:
Define Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
List signs and symptoms of Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
Describe pharmacological treatment of Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
Describe Control and Prevention of Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
Activity: Buzzing
What
is Mycoplasma
Synoviae
Infection in Poultry?
Definition of Mycoplasma
Synoviae
Infection and
Staphylococcosis
in Poultry
Infectious synovitis is an acute or chronic mycoplasmosis of chicken and turkeys caused by
Mycoplasma synoviae
, which is characterized by inflammation of synovial membranes, and usually, by exudates in the joints and tendon sheaths.
Most outbreaks occur in young broiler chicken, though adults are also infected.
Transovarian
transmission is the most important route of infection
Infection also spreads via the respiratory tract
Signs
and Symptoms of Mycoplasma
Synoviae
Infection in Poultry
Lethargy
whereby the affected birds lie on the floor
Head parts are swollen
the hocks or food pads are swollen
At post mortem, the joints contain sticky, viscid, gray to yellow, characteristic exudates.
Parenchymatous
organs become swollen and diarrhea may occur
Pharmacological
treatment of Mycoplasma
Synoviae
Infection in Poultry
Several
drugs are used; but the most effective are the following
Tylosin
litres
(0.05%) of drinking water for the first 3 days of life; repeated for 1 to 7 days every 5 weeks depending on the severity of the infection, or
Erythromycin, 500mg/gallon of water, for 7 days, or
tonne
of feed, for 5 days
Activity:
Brainstorming
•What
are the prevention and control measures against Mycoplasma
Synoviae
Infection in Poultry?
Prevention and Control of Mycoplasma
Synoviae
Infection in Poultry
Maintain
seronegative stock, because the organism is transmitted via eggs.
Eradication of this infection is also possible by purchase of uninfected chicks, all-in/all-out production, and biosecurity.
In valuable breeding stock, treat eggs with
tylosin
or heat
Key Points
Infectious
synovitis is an acute or chronic
mycoplasmosis
of chicken and turkeys caused by
Mycoplasma
synoviae
The first signs of infectious synovitis include pale-bluish head parts and lameness in many birds with a tendency to sit
The more severely affected birds are depressed and found resting around feeders and waterers
Eradication of this infection is also possible by
purshasing
uninfected chicks, all-in/all-out production, and biosecurity
Evaluation
What
is Mycoplasma
Synoviae
Infection in Poultry?
What are the common signs and symptoms of Mycoplasma
Synoviae
Infection in Poultry?
What is the pharmacological treatment of Mycoplasma
Synoviae
Infection in Poultry?
What are the control measures against Mycoplasma
Synoviae
Infection in Poultry?
REFER
Students to
Handout 26.1
:
For pharmacotherapy of
Staphylococcosis
in poultry,
References
Riviere
J. E.,
Papich
M. G. (2009).
Veterinary Pharmacology and Therapeutics
(9
th
Ed) Iowa, Wiley-
Blackwel
Publishers
Hsu
W. H. (2008).
Handbook of Veterinary Pharmacology
(1
st
Ed) Iowa, Wiley-
Blackwel
Publishers
Kuafmann
J, (1996).
Parasitic infections of domestic animals
, (2
nd
ed
).Berlin,
Birkhäuser
Verlag
Press
Hoare
E. W. (2013).
A manual veterinary therapeutics & pharmacology
(2
nd
ed
),New
York, Forgotten Books
Press
Maddison
. J. (
ed
) (2008).
Small Animal Clinical Pharmacology
, (2nd
ed
). Philadelphia, Saunders Elsevier Limited
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