Pharmacotherapy of Infectious Bursal (Gumboro) Disease in Poultry
PST 06107
Basic Veterinary Pharmacology
Session 23: Pharmacotherapy of Infectious Bursal (
Gumboro
) Disease in Poultry
Learning Tasks
By
the end of this session students are expected to be able to:
Define Infectious Bursal (
Gumboro
) Disease in Poultry
List signs and symptoms of Infectious Bursal (
Gumboro
) Disease in Poultry
Describe pharmacological treatment of Infectious Bursal (
Gumboro
) Disease in Poultry
Describe Control and Prevention of Infectious Bursal (
Gumboro
) Disease in Poultry
Activity: Buzzing
What
is Infectious Bursal (
Gumboro
) Disease? ?
Definition
of Infectious Bursal (
Gumboro
) Disease in Poultry
Infectious bursal disease also known as Gumboro disease, is an acute, contagious, viral disease of young chickens characterized by;
Diarrhea
Vent pecking
Trembling
Incoordination followed by atrophy of the Bursa of
Fabricius
and by a variable degree of immune suppression
Definition of Infectious Bursal (
Gumboro
) Disease in
Poultry Cont.….
The virus, belongs to the
Birnaviridae
family and is resistant to most disinfectants and environmental factors and persists for months in contaminated house, for weeks in water, feed and droppings
The virus is shed in the feces and transferred by fomites (direct and indirect contact)
Chickens at 3-6 weeks age are most susceptible and show clinical disease.
The diseases is subclinical at younger age
Signs
and Symptoms of Infectious Bursal (
Gumboro
) Disease in Poultry
The
clinical signs include blood stained feces and straining
Initially necropsy, the bursa may be twice as large as the normal size then it becomes atrophied and reddened
haemorrhages
may occur in thigh and pectoral muscles
Loss of appetite and rapid sudden onset of water consumption may also occurs
Watery droppings and ruffled feather may be observed
Pharmacological Treatment of Infectious Bursal (
Gumboro
) Disease in Poultry
No
specific treatment available
Drug & to protect from secondary
bactiriae
Activity:
Brainstorming
are the prevention and control measures
for
Infectious
Bursal (
Gumboro
) Disease
?
Prevention and Control of Infectious Bursal (
Gumboro
) Disease in Poultry
Depopulation
and rigorous disinfection of contaminated farms
Live vaccines of chick-embryo or cell-culture origin and of varying virulence can be administered by eye drop, drinking water, or SC routes at 1-21 days of age
Vaccination of breeding flocks one or more times during the growing period, first with a live vaccine and again just before egg production with an oil-
adjuvanted
, inactivated vaccine
Key Points
Infectious
bursal disease (IBD) is seen in domestic chickens worldwide
IBD is caused by a
birnavirus
(infectious bursal disease virus; IBDV) that is most readily isolated from the bursa of
Fabricius
but may be isolated from other organs
Chickens are most susceptible to clinical disease at 3–6
wk
of age when immature B cells populate the bursa and maternal immunity has waned
There is no treatment. Rigorous disinfection of contaminated farms after depopulation has achieved limited success.
Evaluation
What
is Infectious Bursal (
Gumboro
) Disease?
What are the common signs and symptoms Infectious Bursal (
Gumboro
) Disease?
What is the pharmacological treatment of Infectious Bursal (
Gumboro
) Disease?
What are the control measures against Infectious Bursal (
Gumboro
) Disease?
References
Riviere
J. E.,
Papich
M. G. (2009).
Veterinary Pharmacology and Therapeutics
(9
th
Ed) Iowa, Wiley-
Blackwel
Publishers
Hsu
W. H. (2008).
Handbook of Veterinary Pharmacology
(1
st
Ed) Iowa, Wiley-
Blackwel
Publishers
Kuafmann
J, (1996).
Parasitic infections of domestic animals
, (2
nd
ed
).Berlin,
Birkhäuser
Verlag
Press
Hoare
E. W. (2013).
A manual veterinary therapeutics & pharmacology
(2
nd
ed
),New
York, Forgotten Books
Press
Maddison
. J. (
ed
) (2008).
Small Animal Clinical Pharmacology
, (2nd
ed
). Philadelphia, Saunders Elsevier Limited
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