Pharmacotherapy of Coccidiosis in Cattle, Goat and Pig – PST06107 Basic Veterinary Pharmacology

NTA Level 6 • Semester 1 • PST06107

Pharmacotherapy of Coccidiosis in Cattle, Goat and Pig

Basic Veterinary Pharmacology • Source Session/Topic 6
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PST 06107

Basic Veterinary Pharmacology

Session 6: Pharmacotherapy of Coccidiosis in Cattle, Goat and Pig

Learning

Tasks

By

the end of this session students are expected to be able to:

Define Coccidiosis disease in Cattle, Goat and Pig

List signs and symptoms of Coccidiosis in Cattle, Goat and Pig

Describe pharmacological treatment of Coccidiosis in Cattle, Goat and Pig

Describe dose, dosage and course of drugs used to treat Coccidiosis in Cattle, Goat and Pigs

List contraindications of drugs used to treat Coccidiosis in Cattle. Goat and Pig

List common side effects and adverse effects of drugs used to treat Coccidiosis in Cattle, Goat and Pigs

Describe Control and Prevention of Coccidiosis in Cattle, Goat and Pigs

Activity: Buzzing

What

is

Coccidiosis

?

Definition

of Coccidiosis in Cattle

Cocciodiosis

, a protozoan parasite of cattle, is caused by the genus Eimeria

The most common species affecting cattle include

E.

bovis

,

E

zuernii

, and

E

auburnensis

The disease is common in young cattle up to two years old.

Signs and symptoms of Coccidiosis in cattle

Watery

feces, with little or no blood and shreds of epithelium and mucus

Animals may die from secondary bacterial complications or concurrent infections (e.g. corona virus infection) that develop ;

Fever

become

anorectic

Signs and symptoms of Coccidiosis in

cattle

Cont

depressed

dehydrated

loss of weight

Eimeria

zuernii

is highly pathogenic causing bloody diarrhea

Coccidiosis in cattle

Pharmacological Treatment of Coccidiosis in

Cattle

Amprolium

10 mg/kg, q 24 h, PO for 5 days, or
Sulfamethazine 50-110 mg/kg, q 24 h, PO for 4 days, or

Decoquinate 167g/10kg of feed for 28 days, or

Monensin 100-360 mg/head/day PO for 7 days

Do not mix with drugs having similar action

Avoid direct contact with skin and wash thoroughly after handling the product

Supportive therapy

The most effective treatment for the already sick animal is fluids

Contraindications in Treatment of Coccidiosis in Cattle

Sulfamethazine

Allergy and hypersensitivity

Decoquinate

Do not use in cases of hypersensitivity to the active substance or to any of the excipients

Monensin

Hypersensitivity to

Monensin

Common

Side Effects and Adverse Drug Reactions of Drugs Used in Treatment of Coccidiosis in Cattle

Monensin

high dose may result in reduced weight gain,

Reduced voluntary feed intake

Reduced milk fat percentage

Increased incidence and treatment of cystic ovaries and metritis

Reduced conception rates

Activity:

Brainstorming

What

are the prevention and control measures for Coccidiosis in Cattle?

Prevention and Control of Coccidiosis in Cattle

Prophylaxis

Amprolium 5-10 mg/kg q 24 h for 21 days, PO
Monensin 1 mg/kg in feed for 30 days

Control

Housing and ventilation deficiencies should be corrected

Do not mix different age groups of calves, avoid fecal contamination of feed.

Isolation of the affected animal(s) to prevent increased contamination of the premises

Key Points

Coccidiosis

is caused by protozoan parasites of

Eimeria

species

The most effective treatment for the already

sickcattle

is supportive therapy (fluids) and antibiotics to ward off secondary infections

Prevention focuses on preventing

fecal

contamination of the cattle’s environment, feed and water

Evaluation

What

is Coccidiosis?

What are the common signs and symptoms of Coccidiosis?

What is the pharmacological treatment of Coccidiosis?

What are the control measures against Coccidiosis?

REFER

Students to Handout 6.1 For pharmacotherapy of Coccidiosis in Goats,: Pharmacotherapy of Coccidiosis in

Goats

REFER

Students to Handout 6.2: For pharmacotherapy of Coccidiosis in Pigs, Pharmacotherapy of Coccidiosis in Pigs

References

Riviere

J. E.,

Papich

M. G. (2009).

Veterinary Pharmacology and Therapeutics

(9

th

Ed) Iowa, Wiley-

Blackwel

Publishers

Hsu

W. H. (2008).

Handbook of Veterinary Pharmacology

(1

st

Ed) Iowa, Wiley-

Blackwel

Publishers

Kuafmann

J, (1996).

Parasitic infections of domestic animals

, (2

nd

ed

).Berlin,

Birkhäuser

Verlag

Press

Hoare

E. W. (2013).

A manual veterinary therapeutics & pharmacology

(2

nd

ed

),New

York, Forgotten Books

Press

Maddison

. J. (

ed

) (2008).

Small Animal Clinical Pharmacology

, (2nd

ed

). Philadelphia, Saunders Elsevier Limited

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