Pharmacotherapy of Actinobacillosis and Actinomycosis in Cattle and Goat
PST 06107
Basic Veterinary Pharmacology
Session 3: Pharmacotherapy of Actinobacillosis and
Actinomycosis
in Cattle and Goat
Learning Tasks
By the end of this session students are expected to be able to:
Define Actinobacillosis and Actinomycosis in Cattle and Goat
List signs and symptoms of Actinobacillosis and Actinomycosis in Cattle and Goat
Describe pharmacological treatment of Actinobacillosis and Actinomycosis in Cattle and Goat
Describe dose, dosage and course of drugs used to treat Actinobacillosis and Actinomycosis in Cattle and Goat
List contraindications of drugs used in treatment of Actinobacillosis and Actinomycosis in Cattle and Goat
List common side effects and adverse effects of drugs used in treatment of Actinobacillosis and Actinomycosis Cattle and Goat
Describe Control and Prevention of Actinobacillosis and Actinomycosis in Cattle and Goat
Activity: Buzzing
What is Actinobacillosis?
Definition of Actinobacillosis and
Actinomycosis
in Cattle and Goat
Actinobacillosis
Actinobacillosis also known as wooden tongue is a sporadic disease of cattle and sheep commonly caused by the bacteria,
A.
lignieresii
It is characterized by nodular abscission of soft tissues
Definition of Actinobacillosis and
Actinomycosis
in Cattle and Goat Cont..
Signs and Symptoms of Actinobacillosis in Cattle and Goat
Actinobacillosis
The tongue shows hard tumorous abscess, and similar lesions are found in the stomach and other soft tissues of the head, neck, and limbs, and occasionally in the lungs, pleura, udder, and subcutaneous tissue
Abscesses forming nodules may ulcerate and discharge viscous, white faintly green exudates that may contain small
grayish
white granules
Signs and Symptoms of Actinobacillosis in Cattle and Goat
Overview of Actinobacillosis in the tongue of the cow
Pharmacological treatment of Actinobacillosis in Cattle and Goat
First line
Streptomycin or
dihydrostreptomycin
sulfate
Alternative
Sulfadimidine
Surgical debridement and flushing with iodine
Pharmacological treatment of Actinobacillosis in Cattle and Goat Cont..
Contraindications
Streptomycin or dihydrostreptomycin sulphate is contraindicated to myasthenia gravis
Sulfadimidine
sodium is contraindicated in pregnant and lactating animals
Common Side Effects and Adverse Drug Reactions of Drugs Used in Treatment of Actinobacillosis
Streptomycin or dihydrostreptomycin
sulfate
Nephrotoxicity
Ototoxicity
Neuromuscular blockage
At higher dosage calves may develop
diarrhea
.
Sulfadimidine
sodium
Crystallization in urinary tract,
Cutaneous eruption
Activity:
Brainstorming
What are the preventive measures for Actinobacillosis in Cattle?
Prevention and control of Actinobacillosis in cattle and goat
No vaccines are available.
Control of Actinobacillosis is best achieved by early recognition and prompt treatment of cases
Isolation
Disposal of animals with disease is recommended.
Key Points
Actinobacillosis refers to a group of diseases caused by gram-negative coccobacilli in the genus
Actinobacillus
Streptomycin is considered the treatment of choice;
tetracylcines
and
tilmicosin
are also effective.
Treatment may also involves administration of antibiotics and potassium iodide orally or intravenously
There in no vaccine against
A.
lignieresii
disease
Evaluation
What is Actinobacillosis?
What are the signs and symptoms of Actinobacillosis?
What is the pharmacological treatment of Actinobacillosis?
For pharmacotherapy of
actinomycosis
in Cattle and Goat, REFER Students to Handout 3.1: Pharmacotherapy of
Actinomycosis
in Cattle and Goat.
References
Riviere
J. E.,
Papich
M. G. (2009).
Veterinary Pharmacology and Therapeutics
(9
th
Ed) Iowa, Wiley-
Blackwel
Publishers
Hsu W. H. (2008).
Handbook of Veterinary Pharmacology
(1
st
Ed) Iowa, Wiley-
Blackwel
Publishers
Kuafmann
J, (1996).
Parasitic infections of domestic animals
, (2
nd
ed
).Berlin,
Birkhäuser
Verlag
Press
Hoare E. W. (2013).
A manual veterinary therapeutics & pharmacology
(2
nd
ed
),New York, Forgotten Books Press
Maddison. J. (
ed
) (2008).
Small Animal Clinical Pharmacology
, (2nd
ed
). Philadelphia, Saunders Elsevier Limited
Unataka kutumiwa notes hizi kupitia WhatsApp?Kwa notes zilizopangiliwa vizuri kwa kusoma offline au PDF, bonyeza kitufe hapa chini. Ujumbe wenye Level, Semester, Module na Topic utaandaliwa moja kwa moja.TUMIWA NOTES WHATSAPP
