Classification of Organic Compounds – PST05106 Pharmaceutical Organic Chemistry

NTA Level 5 • Semester 1 • PST05106

Classification of Organic Compounds

Pharmaceutical Organic Chemistry • Source Session/Topic 2
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 2: Classification of Organic Compounds.

Total Session Time: 60 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• Classify organic compounds

Resources Needed:

• Flip charts, marker pens, and masking tape.
• Black/white board and chalk/whiteboard markers.

SESSION OVERVIEW

|Step |Time |Activity/ |Content |

| | |Method | |

|1 |05 minutes |Presentation |Introduction, Learning Tasks |

|2 |40 minutes |Presentation |Classification of Organic compounds |

| | |Group | |

| | |Discussion | |

|3 |05 minutes |Presentation |Key Points |

| 4 |10 minutes |Presentation |Evaluation |

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify.

ASK students if they have any questions before continuing.

STEP 2: Classification of Organic Compounds (40 minutes)

| |

|Activity: Small Group Discussion (20 minutes). |

| |

|DIVIDE students into small manageable groups. |

| |

|ASK students to discuss on the following question. |

|How do we classify Organic Compounds? |

| |

|ALLOW students to discuss for 15 minutes. |

| |

|ALLOW few groups to present and the rest to add points not mentioned. |

| |

|CLARIFY and SUMMARIZE by using the contents below |

• Organic compounds are classified as follows:

o Acyclic or open chain compounds,

o Alicyclic or closed chain or ring compounds,

o Aromatic compounds and

o Heterocyclic aromatic compounds

Acyclic or open chain compounds:

o These compounds are also known as aliphatic compounds, they have

branched or straight chains. Following are the examples in this

category.

[pic]

• Alicyclic or closed chain or ring compounds:

o These are cyclic compounds which contain carbon atoms connected to

each other in a ring (homocyclic).

o When atoms other than carbon are also present then it is called as

heterocyclic. Examples of this type are as follows:

[pic]

• Aromatic compounds

o They are a special type of compounds which contain benzene and other

ring related compounds.

o Similar to alicyclic, they can also have heteroatoms in the ring.

o Such compounds are called as heterocyclic aromatic compounds.

o Some of the examples are as follows:

▪ Benzenoid aromatic compounds

[pic]

▪ Non-benzenoid aromatic compounds

[pic]

Eg Tropolone

• Heterocyclic aromatic compounds

[pic]

• Organic compounds are also classified as saturated and unsaturated

hydrocarbons.

o Hydrocarbons are compounds containing carbon and hydrogen

o Saturated hydrocarbons are those in which adjacent carbon atoms are

joined by a single covalent bond and all other bonds are satisfied

by hydrogen.

o Unsaturated hydrocarbons have at least two carbon atoms that are

joined by more than one covalent bond and all remaining bonds are

satisfied by hydrogen.

[pic] [pic]

Fig.1. Diagrammatic Classification of Organic Compounds

[pic]

STEP 3: Key Points (05 minutes).

• Organic compounds are classified as Acyclic or open chain compounds,

Alicyclic or closed chain or ring compounds, Aromatic compounds and

Heterocyclic aromatic compounds.

• Organic compounds are also classified as saturated and unsaturated

hydrocarbons.

STEP 4: Evaluation (10 minutes).

• What are Acyclic or open chain compounds?
• What are Alicyclic or closed chain or ring compounds?
• What are Aromatic compounds?
• What are Heterocyclic aromatic compounds?
• What are saturated and unsaturated hydrocarbons?

References

Ternay, A.L (1976). Contemporary Organic Chemistry. Philadelphia, United

States: W.B. Saunders Co.

Morrison R.T and Boyd R N (1997). Organic Chemistry (6th Ed.). New Delhi,

India: Prentice Hall of India

Graham Solomon et al (2014). Organic Chemistry (11th Ed.). New Jeysey,

United States: John Willey and Sons.

Rama R. N. (2005). Principles of Pharmaceutical Organic Chemistry. New

Delhi, India: MacMillan Publishers

Bruice Y (2013). Organic Chemistry (7th ed.). New York, United States:

Prentice Hall Pearson.

Delgado J. N. Et al (1998). Wilson and Gisvold's Textbook of Organic

Medicinal and Pharmaceutical Chemistry (10th Ed.). California, United

States: Lippincott Williams

Bhassin S.K, Gupta R.(2013). Pharmaceutical organic chemistry (E-book

Kindle edition). New Delhi, India: Elsevier Publishing Services

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