Pharyngitis – PST05103 Pharmaceutical Microbiology

NTA Level 5 • Semester 1 • PST05103

Pharyngitis

Pharmaceutical Microbiology • Source Session/Topic 10
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 10: Pharyngitis

Total Session Time: 60 minutes

Pre-requisites

• Human anatomy and physiology

Students Learning Tasks

By the end of this session students are expected to be able to:

• Describe common pharyngitis (causative agents, transmission, signs and

symptoms)

• Describe treatment, prevention and control of pharingitis

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers

SESSION OVERVIEW

|Step |Time |Activity/ |Content |

| | |Method | |

|1 |5 minutes |Presentation |Introduction, Learning Tasks |

|2 |15 minutes |Presentation |Cause and Transmission Pharyngitis|

|3 |15 minutes |Presentation |Signs and Symptoms of Pharyngitis |

|4 |15 minutes |Presentation |Treatment, Prevention and Control |

| | | |of Pharyngitis |

|5 |5 minutes |Presentation |Key Points |

| 6|5 minutes |Presentation |Evaluation |

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning tasks and clarify

ASK students if they have any questions before continuing

STEP 2: Cause and Transmission of Pharyngitis (15 minutes)

• Pharyngitis (or sore throat) is an inflammation of the pharynx involving

lymphoid tissues of the posterior pharynx and lateral pharyngeal bands

• Pharyngitis can be caused by bacterial, viral and fungal infections as

well as noninfectious etiologies such as smoking

• Most cases are due to viral infections and accompany a common cold or

influenza.

• Type A coxsackie viruses can cause a severe ulcerative pharyngitis in

children (herpangina), and adenovirus and herpes simplex virus, although

less common, also can cause severe pharyngitis

• Pharyngitis is a common symptom of Epstein-Barr virus and

cytomegalovirus infections.

• Group A beta-hemolytic streptococcus or Streptococcus pyogenes is the

most important bacterial agent associated with acute pharyngitis and

tonsillitis

o These bacteria attach the mucosa of the upper respiratory tract

STEP 3: Signs and Symptoms of Pharyngitis (15 minutes)

• Pharyngitis usually presents with a red, sore, or “scratchy” throat
• Discomfort or pain in the throat, especially in the morning
• Sensation of foreign body in the throat
• An inflammatory exudate or membranes may cover the tonsils and tonsillar

pillars

o Cough

• Vesicles or ulcers may also be seen on the pharyngeal walls
• Depending on the pathogen, fever and systemic manifestations such as

malaise, myalgia, or headache may be present

• Anterior cervical lymphadenopathy is common in bacterial pharyngitis and

difficulty in swallowing may be present.

STEP 4: Treatment, Prevention and Control of Pharyngitis (15 minutes)

• Symptomatic treatment e.g. Paracetamol to control fever is recommended

for viral pharyngitis

• The exception is herpes simplex virus infection, which can be treated

with acyclovir if clinically warranted or if diagnosed in

immunocompromised patients

• The specific antibacterial agents will depend on the causative organism,

but penicillin G is the therapy of choice for streptococcal pharyngitis

• Warm saline gargle (especially in the morning) is also useful to sooth

and relieve discomfort

• Mycoplasma and chlamydial infections respond to erythromycin,

tetracyclines and the new macrolides

• \Preventive measures include personal hygiene

STEP 5: Key Points (5 minutes)

• Pharyngitis is an inflammation of the pharynx involving lymphoid tissues

of the posterior pharynx and lateral pharyngeal bands

• Pharyngitis can be caused by bacterial, viral and fungal infections as

well as noninfectious etiologies such as smoking

• Group A beta-hemolytic streptococcus or Streptococcus pyogenes is the

most important bacterial agent associated with acute pharyngitis and

tonsillitis

• Pharyngitis usually presents with a red, sore, or “scratchy” throat

STEP 6: Evaluation (5 minutes)

• What is sore throat?
• How is sore throat treated?
• How is pharyngitis transmitted?

References

Hugo and Russell (2011), Pharmaceutical Microbiology 8th Edition, Willey-

Blackwel publications

Karen C. Carroll et al (2013); Jawetz, Melnick and Adelberg’s Medical

Microbiology 26th Ed. McGraw Hill Co. Inc.

Greenwood et al (2012); Medical Microbiology, 18th edition Churchill

Livingston

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