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Introduction to Pharmaceutical Compounding – PST04209 Compounding of Pharmaceutical Preparations

NTA Level 4 • Semester 2 • PST04209

Introduction to Pharmaceutical Compounding

Compounding of Pharmaceutical Preparations • Source Session/Topic 1
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 1: Introduction to Pharmaceutical Compounding

Total Session Time: 60 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• Describe Historical Background of Compounding
• Define Pharmaceutical Compounding
• Explain Reasons for Compounding in Pharmacy practice

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board, chalk and whiteboard markers
• LCD projector and computer

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Tasks

15 minutes Presentation

2 Historical Background of Compounding

Buzzing

10 minutes Presentation

3 Definition of Pharmaceutical Compounding

Buzzing

20 minutes Presentation Reasons for Compounding in Pharmacy

4

Practice

5 05 minutes Presentation Key Points

6 05 minutes Presentation Evaluation

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 1

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning objectives and clarify

ASK students if they have any questions before continuing.

STEP 2: Historical Background of Compounding (15 minutes)

Activity: Buzzing (5 minutes)

ASK students to pair up and buzz on the following question for 2 minutes

• What is the origin of Compounding?

ALLOW few pairs to respond and let other pairs to add on points not mentioned

WRITE their response on the flip chart/board

CLARIFY and SUMMARIZE by using the content below

• Compounding has its origins since the beginning of the profession of pharmacy itself.
• The profession of pharmacy is as old as mankind, it has been a part of everyday life.
• The oldest settlements support the contention that prehistoric peoples gathered plants for

medicinal purposes.

• By trial and error, the folk knowledge of the healing properties of certain natural substances

grew

• Compounded Medications were the standard means of providing prescription medications

prior to medications being mass produced in high volume by large pharmaceutical

manufacturers. .

• In the last few decades, patient and physicians have realized that not all patients can tolerate

commercial, “off the shelf” medications. And hence demand for professional compounding

to meet the required dosage strengths, dosage forms.

• Patients often experience better outcomes with customized compounded prescriptions that

are formulated specifically for them.

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 2

STEP 3: Definition of Pharmaceutical Compounding (10 minutes)

Activity: Brainstorming (10 minutes)

Ask students to brainstorm on the following question:

• What is pharmaceutical compounding?

ALLOW few students to respond?

WRITE their responses on the flip chart/ board

CLARIFY and SUMMARISE by using the content below

• Pharmaceutical compounding is the art and science of preparing a particular pharmaceutical

product by combining appropriate ingredients using various tools to meet the unique need of

a patient. Or

• Compounding is defined as the art and science of creating personalized medications for

patient. Or

• The pharmaceutical compounding includes preparation, mixing, assembling, altering,

packaging, and labeling of a drug, drug-delivery device, or device in accordance with a

licensed practitioner‟s prescription, medication order, or initiative based on the practitioner/

patient/ pharmacist/compounder relationship in the course of professional practice.

STEP 4: Reasons for Compounding in Pharmacy Practice (20 minutes)

The following are reasons for compounding:

• To adjust strength or dosage
• To flavour a medication (i.e. to make it palatable for a child)
• To reformulate the drug to exclude an unwanted , nonessential ingredient
• To change the form of the medication for patients who, for example, have difficulty in

swallowing or experience stomach upset when taking oral medication.

• To ensure the patient is getting the right drug

STEP 5: Key Points (5 minutes)

• Compounding has its origins since the beginning of the profession of pharmacy itself.
• The profession of pharmacy is as old as man kind
CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 3

• Compounding is defined as the art and science of creating personalized medications for

patient

• The following are reasons for compounding;

o To adjust strength or dosage

o To flavour a medication (i.e. to make it palatable for a child)

o To reformulate the drug to exclude an unwanted , nonessential ingredient

o To change the form of the medication for patients who, for example, have difficulty

in swallowing or experience stomach upset when taking oral medication.

STEP 6: Evaluation (5 minutes)

• What is the origin of compounding?
• What is pharmaceutical compounding?
• What are the reasons for compounding in pharmacy?
CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 4

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 5

References

Senya, S. S., Mwasha, C. Y. S., Muyinga, A. M., Amiri, R. I., & Mauga, E. A. S. K. (2011).

Tanzania Pharmaceutical Handbook (2nd ed.). Dar es salaam: School of Pharmaceutical

Sciences, Institute of Allied Health Sciences, Muhimbili University of Health and Allied

Health Sciences.

A. J. Winfield, J. A. R., I. Smith. (2009). Pharmaceutical Practice (4th ed.)

Britain, R. P. S. o. G. (1994). The Pharmaceutical Codex (12 ed.). London: London

Pharmaceutical Press.

CMT 04101 Dispensing NTA L 4 Semester 1 Facilitator Guide

Session X: ———— -(Title)———————- 6

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