Anatomy of the Colon: Colon Histology and Tissue Layers (Part 5)
Explore “Colon Histology and Tissue Layers” in this Anatomy of the Colon lesson. Part 5 of the five-part series brings together the source material and lesson topics. Use the contents links to find a section, read the notes, and consult the complete original teaching slides below.

Lesson topics
- Histology of colon
- Histology of Gut.,
- Histology of colon…, (Mucosa)
- Histology of colon…, (Sub Mucosa)
- Histology of colon…, (Muscularis Externa)
Contents
- Read the original document
- Histology of colon
- Histology of Gut.,
- Histology of colon…, (Mucosa)
- Histology of colon…, (Sub Mucosa)
- Histology of colon…, (Muscularis Externa)
- Histology of colon…, (Serosa / adventitia)
- Large Vs Small Intestine
- Enteric plexus
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Read the original source document
Anatomy of the Colon – M. Gowri Shankar: original teaching slides for this study series.
Histology of colon
Histology of colon
Histology of Gut.,
Histology of Gut., Histology of gut consists of, Epithelium Lamina propria Muscularis mucosa Submucosa Muscularis externa Adventitia / Serosa
Histology of colon…, (Mucosa)
Histology of colon…, (Mucosa) Mucosa has, Epithelium – Columnar – absorbs water and ions In lamina propria – has 2 glands Goblet cells – secrete mucous for lubrication Entero endocrine cells – secrete various harmones for regulation of secretion and peristalsis muscularis mucosa – has smooth muscles which facilitates secretion No villi, but crypts of lieberkuhn present
Histology of colon…, (Sub Mucosa)
Histology of colon…, (Sub Mucosa) SubMucosa has, Dense connective tissue Blood vessels and Sub mucosal (Meissner’s Plexus) – regulates submucosal glands and muscularis mucosa Does not has any glands (but in duodenum submucosa has brunners gland, which secrete mucin and alkalizes acid)
Histology of colon…, (Muscularis Externa)
Histology of colon…, (Muscularis Externa) Muscularis externa has, Inner circular and Myenteric plexus (auerbach) Outer Longitudinal layers, which has 2 roles Major role is to form 3 ribbon like bands termed Taenia Coli Minor role in forming a thin layer of muscle coat in colon
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Histology of colon…, (Serosa / adventitia)
Histology of colon…, (Serosa / adventitia) has serous membrane Made of squamous epithelium Helps in lubrication by secreting serous fluid Present in the bowel loops covered by peritoneum So, in large intestine present in transverse and sigmoid colon Adventitia – Attaches organ to the surrounding tissues It covers retro peritoneal part of large intestine (i.e., except trans. And sigmoid colon)
Large Vs Small Intestine
Large Vs Small Intestine
Enteric plexus
Enteric plexus Enteric plexus are of two types, Submucosal (meissners) and Myenteric (Auerbach) Myenteric plexus is responsible for peristaltic contraction and relaxation These plexus are derived from neural crest cells
Review questions and answers
What are the key points about Histology of Gut.,?
Histology of Gut., Histology of gut consists of, Epithelium Lamina propria Muscularis mucosa Submucosa Muscularis externa Adventitia / Serosa
What are the key points about Histology of colon…, (Mucosa)?
Histology of colon…, (Mucosa) Mucosa has, Epithelium – Columnar – absorbs water and ions In lamina propria – has 2 glands Goblet cells – secrete mucous for lubrication Entero endocrine cells – secrete various harmones for regulation of secretion and peristalsis muscularis mucosa – has smooth muscles which facilitates secretion No villi, but crypts of…
What are the key points about Histology of colon…, (Sub Mucosa)?
Histology of colon…, (Sub Mucosa) SubMucosa has, Dense connective tissue Blood vessels and Sub mucosal (Meissner’s Plexus) – regulates submucosal glands and muscularis mucosa Does not has any glands (but in duodenum submucosa has brunners gland, which secrete mucin and alkalizes acid)
What are the key points about Histology of colon…, (Muscularis Externa)?
Histology of colon…, (Muscularis Externa) Muscularis externa has, Inner circular and Myenteric plexus (auerbach) Outer Longitudinal layers, which has 2 roles Major role is to form 3 ribbon like bands termed Taenia Coli Minor role in forming a thin layer of muscle coat in colon
What are the key points about Histology of colon…, (Serosa / adventitia)?
Histology of colon…, (Serosa / adventitia) has serous membrane Made of squamous epithelium Helps in lubrication by secreting serous fluid Present in the bowel loops covered by peritoneum So, in large intestine present in transverse and sigmoid colon Adventitia – Attaches organ to the surrounding tissues It covers retro peritoneal part of large intestine…
More lessons from this document
- Anatomy of the Colon – M. Gowri Shankar — Part 1
- Anatomy of the Colon – M. Gowri Shankar — Part 2
- Anatomy of the Colon – M. Gowri Shankar — Part 3
- Anatomy of the Colon – M. Gowri Shankar — Part 4
- Anatomy of the Colon – M. Gowri Shankar — Part 5
Conclusion
The important points in Histology of colon…, (Mucosa) should be reviewed alongside the definitions, examples and comparisons given above. Continue with the other four articles to cover the rest of the source material.