Gum, Mucilage and Pectins – PST05210 Basic Pharmacognosy

NTA Level 5 • Semester 2 • PST05210

Gum, Mucilage and Pectins

Basic Pharmacognosy • Source Session/Topic 17
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 17: Gum, Mucilage and Pectins

Total Session Time: 120 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• Define gum, mucilage and pectins
• Explain natural source, constituents and uses of Tragacanth gum
• Explain natural source, constituents and uses of Acacia gum
• Explain natural source, constituents and uses of Sterculia gum
• Explain natural source, constituents and uses of Psyllium

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers

SESSION OVERVIEW

|Step |Time |Activity/ |Content |

| | |Method | |

|1 |05 minutes |Presentation |Introduction, Learning Tasks |

|2 |15 minutes |Presentation |Introduction to Gum, Mucilage and |

| | | |Pectins |

|3 |25 minutes |Presentation |Natural Source, Constituents and |

| | | |Uses of Tragacanth Gum |

|4 |25 minutes |Presentation |Natural Source, Constituents and |

| | |Buzzing |Uses of Acacia Gum |

|5 |20 minutes |Presentation |Natural Source, Constituents and |

| | | |Uses of Sterculia Gum |

|6 |20 minutes |Presentation |Natural Source, Constituents and |

| | |Brainstorming |Uses of Psyllium |

|7 |05 minutes |Presentation |Key Points |

|8 |05 minutes |Presentation |Evaluation |

SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning objectives and clarify

ASK students if they have any questions before continuing.

STEP 2: Introduction to Gums, Mucilage and Pectins (15 minutes)

• Gums and mucilage have similar constitutuons and on hydrolysis yield a

mixture of sugar and uronic acids.

• Gums are considered to be pathological products formed upon injury of the

plant or owing to unfavourable conditions such as draught, by a breakdown

of cell walls e.g. tragacanth (extracellular formation gummosis)

• They are insoluble in alcohol but dissolve or swell in water
• Conversely, mucilage are generally normal products of metabolism formed

within the cell (intracellular formation) and may represent storage

material, a water storage reservoir or a protection for germinating

seeds.

• They are often found in quantity in the epidermal cells of leaves, e.g

senna, in seed coats (linseed, psyllium etc.) roots (marshmallow) and

barks (slippery elm)

STEP 3: Natural Source, Constituents and Uses of Tragacanth Gum (25

minutes)

• Definition

o Tragacanth is the “air hardened gummy exudate flowing naturally or

obtained by incision, from the trunk & branches of Astragalus gummifer

(Labillardiere) and certain other spp. of Astragalus

o Tragacanth is the gum that exudes immediately after injury of the plant

occurs and is therefore pre-formed in the plant

• Constituents

o Tragacanthin

o Bassorin

o Sugar

o Uronic acids

• Uses

o Used as a suspending agent for insoluble powders

o Binding agent in pills and tablets

o Emulgent

o A binding agent in food industry

STEP 4: Natural Source, Constituents and Uses of Acacia Gum (25 minutes)

• Definition

o Acacia gum is a dried gum obtained from the stem and branches of Acacia

senegal and some other spp of Acacia (Leguminoseae).

• Constituents

o Arabin (Arabic acid)

o Galactose

o Arabinose

o Rhamnose

o Uronic acids

o Oxidase enzyme

|Activity: Buzzing (5 minutes) |

| |

|ASK students to pair up and buzz on the following question for 2 |

|minutes |

| |

|What are the uses of acacia gum in pharmacy? |

| |

|ALLOW few pairs to respond and let other pairs to add on points not |

|mentioned |

| |

|WRITE their response on the flip chart/board |

| |

|CLARIFY and SUMMARIZE by using the content below |

• Uses

o Used as a general stabilizer in emulsions

o Used in lozenges

o As demulcent

o Used for treatment of diarrhoea, cough and sore throat

o It is also widely used in food and drink industries

STEP 5: Natural Source, Constituents and Uses of Sterculia Gum (20

minutes)

• Definition

o Sterculia gum is the gummy exudate obtained from the tree, Sterculia

urens (Sterculiaceae).

• Constituents

o Uronic acids

o Partial hydrolysis yields

▪ D-galactose
▪ L-rhamnose
▪ D-galacturonic acid
▪ Acetic acid
• Uses

o Granular grades are used as a bulk laxative (second only to psyllium

seed in use as a bulk laxative).

o Powdered gum is used in lozenges, pastes and denture fixture powders.

STEP 6: Natural Source, Constituents and Uses of Psyllium (20 minutes)

• Definition

o Psyllium consists of the dried, ripe seeds of Plantago afra (Plantago

psyllium), P. indica (P. arenaria) and P. ovata (Plantaginaceae)

• Constituents

o Mucilage

o Fixed oil

o Sugars

o Sterols

o Protein

|Activity: Buzzing (5 minutes) |

| |

|ASK students to pair up and buzz on the following question for 2 |

|minutes |

| |

|What are the uses of psyllium? |

| |

|ALLOW few pairs to respond and let other pairs to add on points not |

|mentioned |

| |

|WRITE their response on the flip chart/board |

| |

|CLARIFY and SUMMARIZE by using the content below |

• Uses of Psyllium

o Psyllium is mainly used as a

▪ Dietary fibre to relieve symptoms of both constipation
▪ Mild diarrhea
▪ Occasionally as a food thickener.
▪ Research has shown lowering of blood cholesterol levels in people

with elevated cholesterol,

▪ Lowering of blood glucose levels in people with type 2 diabetes.

STEP 7: Key Points (5 minutes)

• Gums, mucilage and pectins have similar constitutuons and on hydrolysis

yield a mixture of sugar and uronic acids.

• Gums are pathological products formed upon injury of the plant or owing

to unfavourable conditions such as draught, by a breakdown of cell walls

e.g. tragacanth

• Acacia gum is a dried gum obtained from the stem and branches of Acacia

senegal and some other spp of Acacia (Leguminoseae).

STEP 8: Evaluation (5 minutes)

• What is the use of tragacanth in pharmacy?
• What are the uses of Acacia gum?
• What are the reasons for using gums in foods?

References

Trease, G. E., Evans, W. C., & Evans, D. (2009). Trease and Evans

pharmacognosy. London: Saunders.

Joanne Barnes et al (2002), Herbal medicines 3rd Edition: Pharmaceutical

Press

Wallis, T. E. (2005). Textbook of pharmacognosy. New Delhi: CBS.

Robbers, J. E., Speedie, M. K., Tyler, V. E., & Tyler, V. E. (1996).

Pharmacognosy and pharmacobiotechnology. Baltimore: Williams &

Wilkins.

Heinrich, M., Kinghorn, A. D., Maizels, D., Gibbons, S., & Phillipson, J.

D. (2012). Fundamentals of pharmacognosy and phytotherapy. Edinburgh:

Churchill Livingstone/Elsevier.

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