Description of Cough and Cold Preparations – PST04211 Basic Pharmacology

NTA Level 4 • Semester 2 • PST04211

Description of Cough and Cold Preparations

Basic Pharmacology • Source Session/Topic 36
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 36: Description of Cough and Cold Preparations

Total Session Time: 120 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• Define and list the symptoms of common cold and cough
• List indications of Cough and Cold Preparations
• Describe dose, dosage and course of Cough and Cold Preparations
• List Contraindications, side effects, adverse effects, interactions and precautions of

Cough and Cold Preparations

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers
• Overhead projector (OHP) and computer.

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Objectives

Presentation Definition and Symptoms of Common Cold

2 10 minutes

Brainstorming and Cough

Presentation

3 20 minutes Indications of Cough and Cold Preparations

Buzzing

Dose, Dosage and Course of Cough and Cold

4 20 minutes Presentation

Preparations

Presentation Side Effects, Adverse Effects,

5 55 minutes Small Group Contraindications, Interactions and

Discussion Precautions of Cough and Cold Preparations.

6 05 minutes Presentation Key Points

7 05 minutes Presentation Evaluation

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SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Objectives

(05 minutes)

READ or ASK students to read the learning objectives and clarify

ASK students if they have any questions before continuing.

STEP 2: Definition and Symptoms of Common Cold and Cough

(10 minutes)

Activity: Brainstorming (5 minutes)

Ask students to brainstorm on the following questions:

• What causes common cold?
• What are the symptoms of common cold?

ALLOW few students to respond

WRITE their responses on the flip chart/ board

CLARIFY and SUMMARISE by using the content below

• Common cold, also known simply as a cold, is a viral infectious disease of the upper

respiratory tract that primarily affects the nose

• The common cold is a self-limiting condition and must be distinguished from respiratory

infections

• The episodes of the common cold are mostly due to viruses
• The symptoms attribute to the common cold include:

o Cough

o Runny nose

o Blocked nose

o Sore throat

o Fever

o Malaise

o Headache and

o Loss of appetite

• Cough is the expulsion of air from the lungs with a sudden sharp sound.

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STEP 3: Indications of Cough and Cold Preparations (20 minutes)

Activity: Buzzing (5 minutes)

ASK students to pair up and buzz on the following question for 2 minutes

• What are the indications for cough and cold preparations?

ALLOW few pairs to respond and let other pairs to add on points not mentioned

WRITE their response on the flip chart/board

CLARIFY and SUMMARIZE by using the content below

Cough and cold preparations are indicated for: Preparations which contains Codeine,

dextromethorphan (and some other opioids), antihistamines and soothing remedies like cough

syrups are used for cough relief

• Expectorants like guaphensin and mucolytic agents like carbocisteine are used to clean

the thick sputum by reducing the viscosity

• Sympathomimetic preparations like pseudoephedrine, antihistamines like

brompheniramine, saline nose drops and hot fluids are used for nose congestion

• Soothing remedies like syrups and lozenges and topical anaesthetic agents like

benzocaine are used for sore throat relieves

STEP 4: Dose, Dosage and Course of Cough and Cold Preparations

(20 minutes)

• The dose of cough and cold preparations depends on the type of the agent used in a

preparation

• It is important for a health worker to give right information to patients about the dose,

dosage and course of the preparations

• Read the leaflet inserted in a preparation in order to identify the ingredients used, their

doses and dosages

• Most of ingredients in cough and cold preparations are used in 8 hourly, 6 hourly or 4

hourly bases

• Example 60mg of pseudoephedrine is used 3-4 times daily for adults and 30mg 3-4 daily

for children above five years

• The preparations should be used up to two weeks and if there is no improvement see your

doctor for further check-up

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STEP 5: Side Effects, Contraindications, Interactions and Precautions of

Cough and Cold Preparations (55 minutes)

Activity: Small Group Discussion ( 30 minutes)

DIVIDE students into small manageable groups

ASK students to discuss on the following question

• What are Side/adverse effects, contraindications, interactions and precautions of

cough and cold preparations?

ALLOW students to discuss for 15 minutes

ALLOW few groups to present and the rest to add points not mentioned

CLARIFY and SUMMARIZE by using the contents below

• Side effects and adverse effects

o Codeine and dextromethorphan cause nausea, vomiting, constipation, dizziness and

dependence

o Antihistamines cause gastrointestinal disturbances plus central nervous system

disturbances like nausea

o High concentration of alcohol in cough syrups causes sedation by supressing the

cough reflex. Also high concentration of sugar may cause osmotic diarrhoea

o Expectorants cause gastric mucosa irritation, nausea and vomiting

o Mucolytic agents cause bronchospasm, fever and gastrointestinal disturbances

o Ephedrine and pseudoephedrine cause constriction of nasal blood vessels hence

reducing mucosal swelling

o Infants may choke due to aspiration if large volume of normal saline nasal drop is

used

o Lozenges cause aspiration in children

• Contraindications

o Most of mucolytic agents are contraindicated to peptic ulceration, and some in

pregnancy and breast feeding

o Codeine and dextromethorphan should be avoided in patients with acute respiratory

depression

o In intracranial pressure and head injury

• Interactions and Precautions

o Most drug combinations in cough and cold preparations have no rational basis as may

contain ineffective or effective opposing ingredients such as expectorants with cough

suppressants. Such combination should be avoided

o Anaesthetic agents, mucolytic, oral nasal decongestants and antihistamines should be

avoided in young children

o Avoid using more than one preparation at a time

o Avoid the use of codeine cough suppressants in children below 6 years

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o Mucolytic agents should be used with caution with peptic ulceration as may disrupt

gastric mucosa

STEP 6: Key Points (5 minutes)

• The symptoms attribute to the common cold include cough, runny nose, blocked nose,

sore throat, fever, malaise, headache and loss of appetite

• It is important to identify the ingredients in cough and cold preparations in order to give

right indication of them

• The dose of cough and cold preparations depends on the type of the agent used in a

preparation

STEP 7: Evaluation (05 minutes)

• What is cough?
• What are the indications of cough and cold preparation?
• What are the contraindications of codeine?
• Why most of mucolytic agents should be avoided in peptic ulceration?

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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References

Ministry of Health and Social Welfare. (2013). Standard Treatment Guidelines & National

Essential Medicines List Tanzania Mainland (4th ed.). Dar es salaam, Tanzania

government printers.

Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells &, L. Michael. (2014).

Pharmacotherapy: a pathophysiologic approach (9th ed.). New York, McGraw-Hill

Education.

Sally S.R & Jeanne C.S. (2000). Introductory Clinical Pharmacology (6th ed) New York,

Lippincott Williams and Wilkins.

School of Pharmaceutical sciences.( 2011).Tanzania Pharmaceutical Handbook (2nd ed.).

Dar es Salaam, ARDHI University press.

The Royal Pharmaceutical Society of Great Britain. (2007). Martindale, the Extra

Pharmacopoeia (5TH ed). London, pharmaceutical press.

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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