Description of Antinflamatory and Antipruritic Drugs – PST04211 Basic Pharmacology

NTA Level 4 • Semester 2 • PST04211

Description of Antinflamatory and Antipruritic Drugs

Basic Pharmacology • Source Session/Topic 16
Full source-text version: all educational wording from the extracted learning source is retained; only presenter/tutor metadata and web-layout noise are removed, while formatting is improved for readability.

Session 16: Description of Antinflamatory and

Antipruritic Drugs

Total Session Time: 60 minutes

Prerequisites

• None

Learning Tasks

By the end of this session students are expected to be able to:

• List indications of Antinflamatory and Antipruritic Drugs
• List Contraindication of Antinflamatory and Antipruritic Drugs
• Describe dose, dosage and course of Antinflamatory and Antipruritic Drugs
• List side effects and adverse effects of Antinflamatory and Antipruritic Drugs
• Describe interaction and precaution of Antinflamatory and Antipruritic Drugs

Resources Needed:

• Flip charts, marker pens, and masking tape
• Black/white board and chalk/whiteboard markers
• Computer and projector

SESSION OVERVIEW

Activity/

Step Time Content

Method

1 05 minutes Presentation Introduction, Learning Tasks

Presentation/ Indications of Antinflamatory and Antipruritic

2 10 minutes

Buzzing Drugs

Presentation/ Contraindication of Antinflamatory and

3 10minutes

brainstorming Antipruritic Drugs

Dose, Dosage and Course of Antinflamatory

4 10 minutes Presentation

and Antipruritic Drugs

Presentation/ Side Effects and Adverse Effects of

5 10 minutes

brainstorming Antinflamatory and Antipruritic Drugs

Interaction and Precaution Antinflamatory and

6 05minutes Presentation

Antipruritic Drugs

7 05 minutes Presentation Key Points

8 05 minutes Presentation Evaluation

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SESSION CONTENTS

STEP 1: Presentation of Session Title and Learning Tasks (5 minutes)

READ or ASK students to read the learning Tasks and clarify

ASK students if they have any questions before continuing.

STEP 2: Indications of Topical Anti inflammatory and Antipruritic Drugs

(10minutes)

Activity: Buzzing (5minutes)

ASK students to pair up and buzz on the following questions for 5minutes

• What essential topical anti inflammatory and anti pruritic drugs are used in clinical

practice?

• What are the indications of topical anti inflammatory and antipruritic drugs?

ALLOW few learners to respond

WRITE their responses on the flipchart

CLARIFY and SUMMARIZE by using the content below

• Topical anti-inflammatory preparations include betamethazone, hydrocortisone,

clobetasol proprionate.

• They are used in management of:

o Inflammatory conditions of the skin

o Contact dermatitis

o Insects sting

o Eczema

o Psoriasis

• Topical antipruritic agents include calamine, dithranol, tretionin acid, para amino benzoic

acid and calciprotrial. They are used in the management of Pruritus associated with:

o Mild eczematous dermatoses

o Pruritus associated with atopic dermatitis

o Lichen simplex chronicus

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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STEP 3: Contraindication of Topical Anti inflammatory and Antipruritic

Drugs (10 minutes)

Activity: brainstorming (5 minutes)

students to brainstorm on the following question:

• What are the contraindications of topical anti inflammatory and antipruritic drug?

ALLOW few learners to respond

WRITE their responses on the flipchart

CLARIFY and SUMMARIZE by using the content below

• Topical anti-inflammatory preparations are contraindicated to:

o Those who demonstrate hypersensitivity to them

o In untreated infections

o Wide spread plaque psoriasis

• Topical antipruritic are contraindicated to:

o Acute exudative dermatoses

STEP 4: Dose, Dosage and Course of Topical Anti inflammatory and

Antipruritic Drug (10minutes)

• Topical anti-inflammatory preparations:

o Topical preparations should be applied once daily

• Topical antipruritic

o Topical application of the cream should be performed four times daily for up to 8

days of therapy

STEP 5: Side Effects and Adverse Effects of Topical Anti inflammatory

and Antipruritic Drug (10 Minutes)

Activity: brainstorming (5 minutes)

students to brainstorm on the following question:

• What are the side effects and adverse reaction of topical anti inflammatory and

antipruritic drug?

ALLOW few learners to respond

WRITE their responses on the flipchart

CLARIFY and SUMMARIZE by using the content below

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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• Topical anti-inflammatory preparations: (corticosteroids)

o Skin atrophy

o Purpura

o Ecchymosis

o Steroid rosacea,

o Erythema

o Perioral dermatitis

o Steroid acne

o Hypopigmentation

o Hypertrichosis

o Allergic contact dermatitis

• Topical antipruritic

o Transient burning

o Stinging

o Drowsiness

o Rash

o Irritation

STEP 6: Interaction and Precaution of Topical Anti inflammatory and

Antipruritic Drug (5 minutes)

• Topical anti-inflammatory preparations:

o avoid prolonged use on the face and in the children

• Topical antipruritic

o Interact tricyclic antidepressants

o Avoid near eyes

o Avoid in broken skin

Step 7: Key Points (5minutes)

• Topical anti inflammatory are used for the inflammatory condition of the skin
• Topical antipruritic are used for pruritus condition
• The topical anti-inflammatory is contraindicated untreated infection and hypersensitivity
• The topical antipruritic are contraindicated in acute exudative dermatoses

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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STEP 8: Evaluation (5minutes)

• What are indications of anti inflammatory and antipruritic drugs?
• What are the contraindications of anti inflammatory and antipruritic drugs?
• What are the dose, dosage and course of anti inflammatory and antipruritic drugs?
• What are side effects and adverse effects of anti inflammatory and antipruritic drugs?

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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References

Ministry of Health and Social Welfare. ( 2013). Standard Treatment Guidelines & National

Essential Medicines List Tanzania Mainland (4th ed.). Dar es salaam, Tanzania

government printers.

Robert L. T., Gary C. Y., Gary R. M., Barbara G. W., Michael, L.. (2014).

Pharmacotherapy: A Pathophysiologic Approach (9th ed.). New York, McGraw-Hill

Education.

Sally S.R., Jeanne C.S. (2000). Introductory Clinical Pharmacology (6th ed) New York,

Lippincott Williams and Wilkins.

School of Pharmaceutical sciences. (2011).Tanzania Pharmaceutical Handbook (2nd ed.).

Dar es Salaam, ARDHI University press.

The Royal Pharmaceutical Society of Great Britain. (2007). Martindale: The Extra

Pharmacopoeia (5TH ed). London, pharmaceutical press.

The Royal Pharmaceutical Society of Great Britain. (2009). British National Formulary

(59th ed). London, BMJ Group and RPS Publishing.

PST 04211 Basic Pharmacology NTA Level 4 Semester 2 Facilitator Guide

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